Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Reproducibility of Hemodynamic, Cardiac Autonomic Modulation, and Blood Flow Assessments in Patients with Intermittent Claudication

Texto completo
Autor(es):
Andrade-Lima, Aluisio [1] ; Chehuen, Marcel [1] ; Silva Junior, Natan [1] ; Fecchio, Rafael Y. [1] ; Pecanha, Tiago [1] ; Brito, Leandro C. [1] ; Miyasato, Roberto [1] ; Leicht, Anthony S. [2] ; Forjaz, Claudia L. M. [1]
Número total de Autores: 9
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Sch Phys Educ & Sport, Exercise Hemodynam Lab, Sao Paulo - Brazil
[2] James Cook Univ, Coll Healthcare Sci, Townsville, Qld - Australia
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: ANNALS OF VASCULAR SURGERY; v. 57, p. 144-151, MAY 2019.
Citações Web of Science: 0
Resumo

Background: The aim of this study is to identify, in patients with peripheral artery disease and intermittent claudication (IC), the reproducibility of heart rate (HR), blood pressure (BP), rate pressure product, heart rate variability (HRV), and forearm and calf blood flow (BF) and vasodilatory assessments. Methods: Twenty-nine patients with IC underwent test and retest sessions, 8-12 days apart. During each session, HR, BP, HRV, BF, and vasodilatory responses were measured by electrocardiogram, auscultation, spectral analysis of HRV (low frequency, LFR-R; high frequency, HFR-R), and strain gauge plethysmography (baseline BF, post-occlusion BF, post-occlusion area under the curve). Reproducibility was determined by intra-class correlation coefficient (ICC), typical error, coefficient of variation (CV), and limits of agreement. Results: The ICC for HR and BP was >0.8 with CV <9%. For most HRV measures, ICC was >0.9 while CV was <7%, except for LF/HF (ICC = 0.737, CV = 93.8%). The ICC for forearm and calf baseline BF assessments was >0.9 while CV was <19%; variable ICC and CV for vasodilatory responses were exhibited for calf (0.653-0.770, 35.2-37.7%) and forearm (0.169-0.265, 46.2-55.5%). Conclusions: In male patients with IC, systemic hemodynamics (HR and BP), cardiac autonomic modulation (LFR-R and HFR-R), and forearm and calf baseline BF assessments exhibited excellent reproducibility, whereas the level of reproducibility for vasodilatory responses were moderate to poor. Assessment reproducibility has highlighted appropriate clinical tools for the regular monitoring of disease/intervention progression in patients with IC. (AU)

Processo FAPESP: 15/13800-0 - Treinamento de caminhada na claudicação intermitente: respostas em repouso e após exercício máximo.
Beneficiário:Cláudia Lúcia de Moraes Forjaz
Linha de fomento: Auxílio à Pesquisa - Regular