Joint effects of intensity and duration of cigarette smoking on the risk of head and neck cancer: A bivariate spline model approach

Autor(es):Mostrar menos -

Di Credico, Gioia ^{[1, 2]} ; Edefonti, Valeria ^[3] ; Polesel, Jerry ^[4] ; Pauli, Francesco ^[2] ; Torelli, Nicola ^[2] ; Serraino, Diego ^[4] ; Negri, Eva ^[5] ; Luce, Daniele ^[6] ; Stucker, Isabelle ^[7] ; Matsuo, Keitaro ^[8] ; Brennan, Paul ^[9] ; Vilensky, Marta ^[10] ; Fernandez, Leticia ^[11] ; Curado, Maria Paula ^[12] ; Menezes, Ana ^[13] ; Daudt, Alexander W. ^[14] ; Koifman, Rosalina ^[15] ; Wunsch-Filho, Victor ^[16] ; Holcatova, Ivana ^[17] ; Ahrens, Wolfgang ^{[18, 19]} ; Lagiou, Pagona ^[20] ; Simonato, Lorenzo ^[21] ; Richiardi, Lorenzo ^[22] ; Healy, Claire ^[23] ; Kjaerheim, Kristina ^[24] ; Conway, David I. ^[25] ; Macfarlane, Tatiana V. ^{[26, 27]} ; Thomson, Peter ^[28] ; Agudo, Antonio ^[29] ; Znaor, Ariana ^[9] ; Rios, Leonardo F. Boaventura ^[30] ; Toporcov, Tatiana N. ^[16] ; Franceschi, Silvia ^[4] ; Herrero, Rolando ^[9] ; Muscat, Joshua ^[31] ; Olshan, Andrew F. ^[32] ; Zevallos, Jose P. ^[33] ; La Vecchi, Carlo ^[3] ; Winn, Deborah M. ^[34] ; Sturgis, Erich M. ^[35] ; Li, Guojun ^[35] ; Fabianova, Eleonora ^[36] ; Lissowska, Jolanda ^[37] ; Mates, Dana ^[38] ; Rudnai, Peter ^[39] ; Shangina, Oxana ^[40] ; Swiatkowska, Beata ^[41] ; Moysich, Kirsten ^[42] ; Zhang, Zuo-Feng ^[43] ; Morgenstern, Hal ^{[44, 45, 46]} ; Levi, Fabio ^{[47, 48]} ; Smith, Elaine ^[49] ; Lazarus, Philip ^[50] ; Bosetti, Cristina ^[51] ; Garavello, Werner ^[52] ; Kelsey, Karl ^[53] ; McClean, Michael ^[54] ; Ramroth, Heribert ^[55] ; Chen, Chu ^[56] ; Schwartz, Stephen M. ^[56] ; Vaughan, Thomas L. ^[56] ; Zheng, Tongzhang ^[57] ; Menvielle, Gwenn ^[58] ; Boccia, Stefania ^{[59, 60]} ; Cadoni, Gabriella ^{[61, 62]} ; Hayes, Richard B. ^[63] ; Purdue, Mark ^[34] ; Gillison, Maura ^[64] ; Schantz, Stimson ^[65] ; Yu, Guo-Pei ^{[66, 67, 68]} ; Brenner, Hermann ^{[69, 70]} ; D'Souza, Gypsyamber ^[71] ; Gross, Neil D. ^[72] ; Chuang, Shu-Chun ^[73] ; Boffetta, Paolo ^[74] ; Hashibe, Mia ^{[75, 76]} ; Lee, Yuan-Chin Amy ^[75] ; Dal Maso, Luigino ^[4]

Afiliação do(s) autor(es):Mostrar menos -

^[1] Univ Padua, Dept Stat, Padua - Italy

^[2] Univ Trieste, Dept Econ Business Math & Stat, Trieste - Italy

^[3] Univ Milan, Dept Clin Sci & Community Hlth, Branch Med Stat Biometry & Epidemiol GA Maccacaro, Via Venezian 1, I-20133 Milan - Italy

^[4] IRCCS, Ctr Riferimento Oncol Aviano CRO, Canc Epidemiol Unit, Aviano - Italy

^[5] Univ Milan, Dept Biomed & Clin Sci, Milan - Italy

^[6] Univ Rennes, INSERM, EHESP, Irset, UMR S 1085, Pointe A Pitre, Guadeloupe - France

^[7] Univ Paris Saclay, Univ Paris Sud, Canc & Environm Team, Inserm, Ctr Res Epidemiol & Populat Hlth CESP, Villejuif - France

^[8] Aichi Canc Ctr, Res Inst, Nagoya, Aichi - Japan

^[9] Int Agcy Res Canc, Lyon - France

^[10] Univ Buenos Aires, Inst Oncol Angel H Roffo, Buenos Aires, DF - Argentina

^[11] Inst Oncol & Radiobiol, Havana - Cuba

^[12] CIPE ACCAMARGO, Epidemiol, Sao Paulo - Brazil

^[13] Univ Fed Pelotas, Pelotas - Brazil

^[14] Hosp Moinhos de Vento, Porto Alegre, RS - Brazil

^[15] Fundacao Oswaldo Cruz, Escola Nacl Saude Publ, Rio De Janeiro - Brazil

^[16] Univ Sao Paulo, Sch Publ Hlth, Sao Paulo - Brazil

^[17] Charles Univ Prague, Fac Med 1, Inst Hyg & Epidemiol, Prague - Czech Republic

^[18] BIPS, Leibniz Inst Prevent Res & Epidemiol, Bremen - Germany

^[19] Univ Bremen, Fac Math & Comp Sci, Bremen - Germany

^[20] Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens - Greece

^[21] Univ Padua, Dept Cardiovasc & Thorac Sci & Publ Hlth, Padua - Italy

^[22] Univ Turin, Dept Med Sci, Turin - Italy

^[23] Trinity Coll Dublin, Sch Dent Sci, Dublin - Ireland

^[24] Canc Registry Norway, Oslo - Norway

^[25] Univ Glasgow, Sch Med Dent & Nursing, Glasgow, Lanark - Scotland

^[26] Univ Aberdeen, Sch Med Med Sci & Nutr, Aberdeen - Scotland

^[27] Univ Dundee, Sch Med, Dundee - Scotland

^[28] Univ Hong Kong, Hong Kong - Peoples R China

^[29] Inst Catala Oncol, Barcelona - Spain

^[30] Univ Sao Paulo, Sch Med, Sao Paulo - Brazil

^[31] Penn State Coll Med, Hershey, PA - USA

^[32] Univ N Carolina, Sch Publ Hlth, Chapel Hill, NC 27515 - USA

^[33] Washington Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Div Head & Neck Surg Oncol, St Louis, MO 63110 - USA

^[34] NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 - USA

^[35] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 - USA

^[36] Reg Author Publ Hlth, Banska Bystrica - Slovakia

^[37] M Skasodowska Curie Mem Canc Ctr & Inst Oncol, Dept Canc Epidemiol & Prevent, Warsaw - Poland

^[38] Natl Inst Publ Hlth, Bucharest - Romania

^[39] Natl Publ Hlth Inst, Natl Inst Environm Hlth, Budapest - Hungary

^[40] Canc Res Ctr, Moscow - Russia

^[41] Inst Occupat Med, Lodz - Poland

^[42] Roswell Pk Canc Inst, Buffalo, NY 14263 - USA

^[43] Univ Calif Los Angeles, Sch Publ Hlth, Los Angeles, CA 90024 - USA

^[44] Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 - USA

^[45] Univ Michigan, Sch Publ Hlth, Dept Environm Hlth Sci, Ann Arbor, MI 48109 - USA

^[46] Univ Michigan, Sch Med, Dept Urol, Ann Arbor, MI - USA

^[47] Univ Lausanne, Lausanne - Switzerland

^[48] CHU Vaudois, IUMSP, Lausanne - Switzerland

^[49] Univ Iowa, Coll Publ Hlth, Iowa City, IA - USA

^[50] Washington State Univ, Coll Pharm & Pharmaceut Sci, Spokane, WA - USA

^[51] Ist Ric Farmacol Mario Negri IRCCS, Dept Oncol, Milan - Italy

^[52] Univ Milan, Sch Med & Surg, Dept Otorhinolaryngol, Monza - Italy

^[53] Brown Univ, Providence, RI 02912 - USA

^[54] Boston Univ, Sch Publ Hlth, Boston, MA - USA

^[55] Heidelberg Univ, Heidelberg - Germany

^[56] Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Program Epidemiol, 1124 Columbia St, Seattle, WA 98104 - USA

^[57] Brown Univ, Sch Publ Hlth, Dept Epidemiol, Providence, RI 02912 - USA

^[58] Sorbonne Univ, INSERM, Inst Pierre Louis Epidemiol & Sante Publ IPLESP, Dept Social Epidemiol, F-75012 Paris - France

^[59] Fdn Policlin Univ A Gemelli IRCCS, Publ Hlth Area, Dept Woman & Child Hlth & Publ Hlth, Rome - Italy

^[60] Univ Cattolica Sacro Cuore, Ist Sanita Pubbl, Sez Igiene, Rome - Italy

^[61] Fdn Policlin Univ A Gemelli IRCCS, Dipartimento Sci Invecchiamento Neurol Ortoped &, Rome - Italy

^[62] Univ Cattolica Sacro Cuore, Ist Clin Otorinolaringoiatr, Rome - Italy

^[63] NYU, Sch Med, Div Epidemiol, New York, NY - USA

^[64] Univ Texas MD Anderson Canc Ctr, Thoracic Head & Neck Med Oncol, Houston, TX 77030 - USA

^[65] New York Eye & Ear Infirm, New York, NY 10003 - USA

^[66] Peking Univ, Med Informat Ctr, Beijing - Peoples R China

^[67] German Canc Res Ctr, Div Prevent Oncol, Heidelberg - Germany

^[68] Natl Ctr Tumor Dis NCT, Heidelberg - Germany

^[69] German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg - Germany

^[70] German Canc Res Ctr, German Canc Consortium DKTK, Heidelberg - Germany

^[71] Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD - USA

^[72] Univ Texas MD Anderson Canc Ctr, Div Surg, Dept Head & Neck Surg, Houston, TX 77030 - USA

^[73] Natl Hlth Res Inst, Inst Populat Hlth Sci, Zhunan Township - Taiwan

^[74] Icahn Sch Med Mt Sinai, Tisch Canc Inst, New York, NY 10029 - USA

^[75] Univ Utah, Sch Med, Dept Family & Prevent Med, Div Publ Hlth, Salt Lake City, UT 84112 - USA

^[76] Univ Utah, Sch Med, Huntsman Canc Inst, Salt Lake City, UT - USA

• Tipo de documento: Artigo Científico
• Fonte: Oral Oncology; v. 94, p. 47-57, JUL 2019.
• Citações Web of Science: 9

Resumo

Objectives: This study aimed at re-evaluating the strength and shape of the dose-response relationship between the combined (or joint) effect of intensity and duration of cigarette smoking and the risk of head and neck cancer (HNC). We explored this issue considering bivariate spline models, where smoking intensity and duration were treated as interacting continuous exposures. Materials and Methods: We pooled individual-level data from 33 case-control studies (18,260 HNC cases and 29,844 controls) participating in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. In bivariate regression spline models, exposures to cigarette smoking intensity and duration (compared with never smokers) were modeled as a linear piecewise function within a logistic regression also including potential confounders. We jointly estimated the optimal knot locations and regression parameters within the Bayesian framework. Results: For oral-cavity/pharyngeal (OCP) cancers, an odds ratio (OR) > 5 was reached after 30 years in current smokers of similar to 20 or more cigarettes/day. Patterns of OCP cancer risk in current smokers differed across strata of alcohol intensity. For laryngeal cancer, ORs > 20 were found for current smokers of >= 20 cigarettes/day for >= 30 years. In former smokers who quit >= 10 years ago, the ORs were approximately halved for OCP cancers, and similar to 1/3 for laryngeal cancer, as compared to the same levels of intensity and duration in current smokers. Conclusion: Referring to bivariate spline models, this study better quantified the joint effect of intensity and duration of cigarette smoking on HNC risk, further stressing the need of smoking cessation policies. (AU)

• Processo FAPESP: 01/01768-2 - Estudo internacional de fatores ambientais, vírus e câncer de cavidade oral e de laringe
• Beneficiário: José Eluf Neto
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 10/51168-0 - Fatores ambientais, clínicos, histopatológicos e moleculares associados ao desenvolvimento e ao prognóstico de carcinomas epidermoides de cabeça e pescoço
• Beneficiário: Eloiza Helena Tajara da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 04/12054-9 - Busca de marcadores de agressividade em tumores de cabeça e pescoço
• Beneficiário: Eloiza Helena Tajara da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Temático