Activity of sodium trimetaphosphate, associated or not with fluoride, on dual-species biofilms

Autor(es)

Cavazana, Thamires Priscila ^[1] ; Hosida, Thayse Yumi ^[1] ; Pessan, Juliano Pelim ^[1] ; Sampaio, Caio ^[1] ; Monteiro, Douglas Roberto ^[2] ; Botazzo Delbem, Alberto Carlos ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ Unesp, Sch Dent Aracatuba, Dept Pediat Dent & Publ Hlth, Aracatuba, SP - Brazil

^[2] Univ Western Sao Paulo UNOESTE, Grad Program Dent, Presidente Prudente, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: BIOFOULING; v. 35, n. 6 AUG 2019.
• Citações Web of Science: 0

Resumo

This study aimed to evaluate the effect of sodium trimetaphosphate (TMP), either with fluoride (F) or without fluoride, on dual-species biofilms of Streptococcus mutans and Candida albicans. The 72 h biofilms were treated with 0.25%, 0.5%, or 1% TMP solutions, combined or not with 500 ppm F, and analysed by quantification of viable plate counts, metabolic activity, biomass, and extracellular matrix components. Biofilm structure was evaluated by scanning electron microscopy (SEM). TMP significantly reduced the number of S. mutans cells and biomass only when associated to F. Furthermore, fluoride-free TMP promoted significant reductions in biofilm metabolism, while all the tested solutions decreased the contents of the biofilm matrix compared to untreated groups. Regarding biofilm structure, TMP associated with F led to the formation of a less compact biofilm. It was concluded that TMP alone had a reducing effect, mainly on the metabolism and the extracellular matrix components of the biofilms. (AU)

• Processo FAPESP: 16/01752-4 - Efeito do trimetafosfato de sódio, associado ou não ao fluoreto, no biofilme total e fluido do biofilme formado in vitro
• Beneficiário: Thamires Priscila Cavazana
• Modalidade de apoio: Bolsas no Brasil - Mestrado