Enhanced sensitivity of scanning bipolar electrochemical microscopy for O-2 detection

Autor(es)

Santos, Carla Santana ^{[1, 2]} ; Conzuelo, Felipe ^[1] ; Essmann, Vera ^[1] ; Bertotti, Mauro ^[2] ; Schuhmann, Wolfgang ^[1]

Afiliação do(s) autor(es)

^[1] Ruhr Univ Bochum, Fac Chem & Biochem, Analyt Chem Ctr Electrochem Sci CES, Univ Str 150, D-44780 Bochum - Germany

^[2] Univ Sao Paulo, Inst Chem, Dept Fundamental Chem, Av Prof Lineu Prestes 748, BR-05513970 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Analytica Chimica Acta; v. 1087, p. 36-43, DEC 9 2019.
• Citações Web of Science: 0

Resumo

The Scanning Bipolar Electrochemical Microscope (SBECM) allows precise positioning of an electrochemical micro-probe serving as bipolar electrode that can be wirelessly interrogated by coupling the electrochemical detection reaction with an electrochemiluminescent reporting process. As a result, the spatially heterogeneous concentrations of an analyte of interest can be converted in real time into a map of sample reactivity. However, this can only be achieved upon optimization of the analytical performance ensuring adequate sensitivity. Here, we present the evaluation and optimized operation of the SBECM for the detection of small changes in local O-2 concentrations. Parameters for achieving an improved sensitivity as well as possibilities for improving the signal-to-noise ratio in the optical signal readout are evaluated. The capability of the SBECM for O-2 detection is shown at controlled conditions by recording the topography of a patterned sample and monitoring O-2 evolution from a photoelectrocatalyst material. (C) 2019 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 17/12629-1 - Uso de múltiplos eletrodos bipolar como sensores para monitoramento de atividade celular
• Beneficiário: Carla Santana Santos
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado Direto
• Processo FAPESP: 14/22396-6 - Desenvolvimento de microssensor acoplado à microscopia eletroquímica de varredura para a investigação da atividade respiratória mitocondrial
• Beneficiário: Carla Santana Santos
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto