| Texto completo | |
| Autor(es): |
Alves, Vitor S.
[1]
;
Alves-Silva, Helio S.
[1]
;
Orts, Diego J. B.
[2]
;
Ribeiro-Silva, Luisa
[2]
;
Arcisio-Miranda, Manoel
[2]
;
Oliveira, Fernando A.
[3, 1]
Número total de Autores: 6
|
| Afiliação do(s) autor(es): | [1] UFABC, Fed Univ ABC, CMCC, Cellular & Mol Neurobiol Lab LaNeC, Sao Bernardo Do Campo, SP - Brazil
[2] Univ Fed Sao Paulo, UNIFESP, Dept Biofis, Lab Neurobiol Estrutural & Func LaNEF, Sao Paulo, SP - Brazil
[3] Carleton Univ, Dept Neurosci, Ottawa, ON - Canada
Número total de Afiliações: 3
|
| Tipo de documento: | Artigo de Revisão |
| Fonte: | Neuroscience; v. 421, p. 95-111, NOV 21 2019. |
| Citações Web of Science: | 0 |
| Resumo | |
Calcium (Ca2+) is an essential component in intracellular signaling of brain cells, and its control mechanisms are of great interest in biological systems. Ca2+ can signal differently in neurons and glial cells using the same intracellular pathways or cell membrane structural components. These types of machinery are responsible for entry, permanence, and removal of Ca2+ from the cellular environment and are of vital importance for brain homeostasis. This review highlights the importance of Ca2+ in neuronal and glial cell physiology as well as aspects of learning, memory, and Alzheimer's disease, focusing on the involvement of L-type voltage-gated Ca2+ channels. (C) 2019 IBRO. Published by Elsevier Ltd. All rights reserved. (AU) | |
| Processo FAPESP: | 12/50336-2 - Interação entre hipometabolismo, dinâmica do cálcio e excitabilidade neuronal: implicações no processo degenerativo da doença de Alzheimer |
| Beneficiário: | Fernando Augusto de Oliveira Ribeiro |
| Modalidade de apoio: | Auxílio à Pesquisa - Jovens Pesquisadores |
| Processo FAPESP: | 16/17951-6 - OBSERVANDO O pH INTRACELULAR DE CÉLULAS DA MICRÓGLIA |
| Beneficiário: | Manoel de Arcisio Miranda Filho |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 16/50484-2 - Developmental aspects of spatial training on the persistence of memory function during normal and pathological aging |
| Beneficiário: | Fernando Augusto de Oliveira Ribeiro |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |