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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Calcium Signaling in Neurons and Glial Cells: Role of Cav1 channels

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Author(s):
Alves, Vitor S. [1] ; Alves-Silva, Helio S. [1] ; Orts, Diego J. B. [2] ; Ribeiro-Silva, Luisa [2] ; Arcisio-Miranda, Manoel [2] ; Oliveira, Fernando A. [3, 1]
Total Authors: 6
Affiliation:
[1] UFABC, Fed Univ ABC, CMCC, Cellular & Mol Neurobiol Lab LaNeC, Sao Bernardo Do Campo, SP - Brazil
[2] Univ Fed Sao Paulo, UNIFESP, Dept Biofis, Lab Neurobiol Estrutural & Func LaNEF, Sao Paulo, SP - Brazil
[3] Carleton Univ, Dept Neurosci, Ottawa, ON - Canada
Total Affiliations: 3
Document type: Review article
Source: Neuroscience; v. 421, p. 95-111, NOV 21 2019.
Web of Science Citations: 0
Abstract

Calcium (Ca2+) is an essential component in intracellular signaling of brain cells, and its control mechanisms are of great interest in biological systems. Ca2+ can signal differently in neurons and glial cells using the same intracellular pathways or cell membrane structural components. These types of machinery are responsible for entry, permanence, and removal of Ca2+ from the cellular environment and are of vital importance for brain homeostasis. This review highlights the importance of Ca2+ in neuronal and glial cell physiology as well as aspects of learning, memory, and Alzheimer's disease, focusing on the involvement of L-type voltage-gated Ca2+ channels. (C) 2019 IBRO. Published by Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 12/50336-2 - Interaction among hypometabolism, calcium dynamics and neuronal excitability: implications in the degenerative process of Alzheimer's Disease
Grantee:Fernando Augusto de Oliveira Ribeiro
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 16/17951-6 - OBSERVING THE INTRACELLULAR pH OF MICROGLIAL CELLS
Grantee:Manoel de Arcisio Miranda Filho
Support Opportunities: Regular Research Grants
FAPESP's process: 16/50484-2 - Developmental aspects of spatial training on the persistence of memory function during normal and pathological aging
Grantee:Fernando Augusto de Oliveira Ribeiro
Support Opportunities: Regular Research Grants