EVALUATION OF SILICA NANOPARTICLE COLLOIDAL STABILITY WITH A FIBER OPTIC QUASI-ELASTIC LIGHT SCATTERING SENSOR

Autor(es)

Marco César Prado Soares ; Matheus Kauê Gomes ; Egont Alexandre Schenkel ; Matheus dos Santos Rodrigues ; Carlos Kenichi Suzuki ; Lucimara Gaziola de la Torre ; Eric Fujiwara

• Tipo de documento: Artigo Científico
• Fonte: Brazilian Journal of Chemical Engineering; v. 36, n. 4, p. 1519-1534, Dez. 2019.
• Citações Web of Science: 0

Resumo

Abstract Colloidal silica is an important biocompatible, inert and non-toxic material for imaging, therapy, and drug delivery biomedical applications. In this context, the evaluation of colloidal suspensions and their stabilities by a Fiber Optic Quasi-Elastic Light Scattering sensor is proposed. Two different silica nanoparticles were prepared and characterized by scanning electron microscopy and X-ray diffraction, being completely amorphous, with mean diameters of 125 and 159 nm and average specific weight of 1.94 g.cm-3. The nanoparticles were dispersed in deionized water in different concentrations ranging from 0 to 2% (m/m), resulting in suspensions with mean kinematic viscosity of 0.009157 cm².s-1. The sensor showed different sensitivities regarding concentrations and diameters, with an increase in the light intensity dispersion caused by the scattering. A decreasing tendency of the decay rate of the autocorrelation function of the light intensity signal was verified with the variation of pH, and this decay rate also showed an abrupt decrease with the enhancement of the ionic strength, detecting the limits of the colloidal stability. This work presents a simple and reliable methodology for the colloidal assessment in a low-cost and minimally invasive way, easily extendable for different chemical and biological systems. (AU)

• Processo FAPESP: 17/20445-8 - Desenvolvimento de sensor de fibra óptica para monitoramento de reflectância e espalhamento de luz para microfluídica aplicada à biotecnologia
• Beneficiário: Marco César Prado Soares
• Linha de fomento: Bolsas no Brasil - Mestrado
• Processo FAPESP: 17/06190-7 - Caracterização de nanofluidos de dióxido de silício utilizando sensor de fibra óptica
• Beneficiário: Matheus Kaue Gomes
• Linha de fomento: Bolsas no Brasil - Iniciação Científica