Recent Advances in Electrochemical Chalcogen (S/Se)-Functionalization of Organic Molecules

Autor(es)

Martins, Guilherme M. ^{[1, 2]} ; Meirinho, Anne G. ^[3] ; Ahmed, Nisar ^[2] ; Braga, Antonio L. ^[1] ; Mendes, Samuel R. ^[3]

Afiliação do(s) autor(es)

^[1] Univ Fed Santa Catarina, Dept Quim, Labselen, BR-88040900 Florianopolis, SC - Brazil

^[2] Cardiff Univ, Sch Chem, Main Bldg, Pk Pl, Cardiff CF10 3AT, S Glam - Wales

^[3] Univ Estado Santa Catarina, SINCA Dept Quim, BR-89219719 Joinville, SC - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: CHEMELECTROCHEM; v. 6, n. 24, p. 5928-5940, DEC 13 2019.
• Citações Web of Science: 1

Resumo

Achieving advances in the development of clean and efficient synthetic routes has become an important aim in research. In recent years, the search for new sustainable methodologies, notably environmentally benign synthetic procedures, has gained the attention of the scientific community. Electrosynthesis is a tool that has been extensively studied due to its potential application in chemical transformations and it adheres to the principles of green chemistry. Organochalogen compounds form an important class of molecules, since many of them have properties that can be applied in medicine and materials science. Thus, herein we provide a comprehensive and updated overview covering recent advances in the electrochemical C(sp(2))-H bond chalcogenation of activated arenes and heterocycles as well as electrochemical chalcogenation through oxidative cross-coupling reactions and chalcogen-functionalization of alkenes/alkynes. The scope, limitations, and mechanisms are described and discussed, detailing the fundamental aspects and benefits of electrochemistry for the chalcogenation of organic compounds. The content of this Minireview demonstrates that it is possible to provide new synthetic routes and to improve the existing methodologies, to obtain processes more in line with current environmental protection aims. The reader will also find a discussion on the fundamental aspects and benefits of applying electrosynthesis to the assembly and operation of an electrolytic cell. (AU)

• Processo FAPESP: 14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock
• Beneficiário: Arlene Gonçalves Corrêa
• Modalidade de apoio: Auxílio à Pesquisa - Programa Centros de Pesquisa em Engenharia