| Texto completo | |
| Autor(es): |
Mauch, Renan M.
[1]
;
Mansinho, Andrea A. S.
[2]
;
Rocha, Priscilla M. O.
[2]
;
Zaccariotto, Tania R.
[3]
;
Levy, Carlos E.
[3, 4]
;
Nolasco da Silva, Marcos T.
[1]
Número total de Autores: 6
|
| Afiliação do(s) autor(es): | [1] Univ Estadual Campinas, Sch Med Sci, Ctr Invest Pediat, Rua Tessalia Vieira de Camargo 126, BR-13083887 Campinas - Brazil
[2] Univ Estadual Campinas, Sch Med Sci, Dept Pediat, Campinas - Brazil
[3] Univ Estadual Campinas, Teaching Hosp, Div Clin Pathol, Microbiol Lab, Campinas - Brazil
[4] Univ Estadual Campinas, Sch Med Sci, Dept Clin Pathol, Campinas - Brazil
Número total de Afiliações: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | PATHOGENS AND GLOBAL HEALTH; v. 114, n. 2 FEB 2020. |
| Citações Web of Science: | 0 |
| Resumo | |
The aim of this study was to describe the frequency of nontuberculous mycobacteria (NTM) isolation and their related outcomes among pediatric patients of a Brazilian university hospital from 2012 to 2019. NTM were identified in different clinical samples by microbiological culture and molecular-based methods. NTM were isolated from 14 patients, out of whom four (27%) were infected and were treated accordingly. Two were infected with Mycobacterium avium complex (MAC), two with M. abscessus complex (MABSC) and one with M. intracellulare. Two patients had cystic fibrosis-related lung disease and improved after successful NTM eradication. One patient was HIV-positive and died. One patient had severe combined immunodeficiency (SCID)-related pneumonia and is currently being followed-up. We conclude that NTM frequency in our center was low among pediatric patients. Whether this is inherent to Brazilian patients, due to the broad coverage of the Bacille Calmette-Guerin (BCG) vaccine in Brazil, or a result of underdiagnosis remains to be elucidated. (AU) | |
| Processo FAPESP: | 18/10614-0 - Resposta imune inata e adaptativa na persistência da infecção pulmonar por Pseudomonas aeruginosa produtora de biofilme na fibrose cística |
| Beneficiário: | Renan Marrichi Mauch |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |