Non-Alcoholic Cirrhosis and Heart Rate Variability: A Systematic Mini-Review

Autor(es)

do Amaral, Joice Anaize Tonon ^[1] ; Salatini, Renata ^[2] ; Arab, Claudia ^[3] ; Abreu, Luiz Carlos ^[4] ; Valenti, Vitor E. ^[5] ; Monteiro, Carlos B. M. ^[6] ; Tannuri, Uenis ^[7] ; Tannuri, Ana Cristina Aoun ^[7]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Dept Pediat, Fac Med, BR-05403000 Sao Paulo, SP - Brazil

^[2] Univ Sao Paulo, Dept Clin Cirurg, Fac Med, BR-01246903 Sao Paulo, SP - Brazil

^[3] Univ Fed Sao Paulo, Dept Cardiol, BR-04024002 Sao Paulo, SP - Brazil

^[4] Ctr Univ Saude ABC, Lab Escrita Cient & Delineamento Estudos, BR-09060870 Santo Andre, SP - Brazil

^[5] Sao Paulo State Univ, Auton Nervous Syst Ctr, UNESP, BR-17525900 Marilia, SP - Brazil

^[6] Univ Sao Paulo, Escola Artes Ciencias & Humanidades, BR-03828000 Sao Paulo, SP - Brazil

^[7] Univ Sao Paulo, Fac Med, Unidade Cirurgia Pediat & Transplante Figado, Hosp Clin HCFMUSP, Inst Crianca, BR-05403000 Sao Paulo, SP - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: MEDICINA-LITHUANIA; v. 56, n. 3 MAR 2020.
• Citações Web of Science: 0

Resumo

Background and Objectives: Cirrhosis is a liver disease that causes about one million deaths annually worldwide. The estimated cirrhosis prevalence ranges from 4.5-9.5% in the general population. Up to 40% of cirrhotic patients are asymptomatic and may be diagnosed late. Studies have described the importance of the functions of the liver and autonomic nervous system (ANS) and their relationship. There is limited information available on non-alcoholic cirrhosis and heart rate variability (HRV), which is a measure of the ANS. This study aimed to evaluate cardiac autonomic modulation through HRV in non-alcoholic cirrhosis individuals reported in previous observational and clinical trial studies. Materials and Methods: We performed a systematic review according to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statement using the Medline, Scopus, and Web of Science electronic databases. Five studies were identified and reviewed. Results: HRV was decreased in patients with non-alcoholic cirrhosis, even in the first stage. Conclusions: HRV could be used as a complementary method to improve both the diagnosis and prognosis of non-alcoholic cirrhosis. (AU)

• Processo FAPESP: 16/10570-7 - Associação da modulação autonômica cardíaca com PELD em crianças com hepatopatias graves
• Beneficiário: Joice Anaize Tonon do Amaral
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto