Impedimetric electronic tongue based on molybdenum disulfide and graphene oxide for monitoring antibiotics in liquid media

Autor(es)

Facure, Murilo Henrique M. ^{[1, 2]} ; Schneider, Rodrigo ^{[1, 2]} ; dos Santos, Danilo M. ^[2] ; Correa, Daniel S. ^{[1, 2]}

Afiliação do(s) autor(es)

^[1] Fed Univ Sao Carlos UFSCar, Ctr Exact Sci & Technol, Dept Chem, PPGQ, BR-13565905 Sao Carlos, SP - Brazil

^[2] Embrapa Instrumentacao, Nanotechnol Natl Lab Agr LNNA, BR-13560970 Sao Carlos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Talanta; v. 217, SEP 2020.
• Citações Web of Science: 0

Resumo

Antibiotics are considered emerging pollutants which indiscriminate use has led to the development of antibiotic-resistant bacteria, while their improper disposal has caused adverse effects to the environment and human health. Thus, the development of devices or techniques capable of detecting antibiotics with high sensitivity, low detection limits, and reasonable cost becomes of prime importance. In this work, an electronic tongue (e-tongue) based on molybdenum disulfide (MoS2) and graphene oxide (GO) was developed and employed to detect four distinct antibiotics, namely cloxacillin benzathine, erythromycin, streptomycin sulfate, and tetracycline hydrochloride. The five sensing units of the e-tongue were obtained using the drop-casting method to modify gold interdigitated electrodes with MoS2 and GO. Using Principal Component Analysis to process the experimental data allowed the e-tongue to recognize samples contaminated with distinct antibiotics at varied concentrations from 0.5 to 5.0 nmol L-1. Analyses with real samples were also performed using river water and human urine and the electronic tongue was able to differentiate the samples at a nanomolar level. The proposed system represents a sensitive and low-cost alternative for antibiotic analyses in different liquid media. (AU)

• Processo FAPESP: 17/20973-4 - Nanofibras eletrofiadas coaxiais à base de quitosana para a liberação controlada de antibióticos e aplicações no tratamento de lesões periodontais
• Beneficiário: Danilo Martins dos Santos
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 17/10582-8 - Produção e caracterização de quantum dots de grafeno e sua aplicação em sensores químicos
• Beneficiário: Murilo Henrique Moreira Facure
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 18/18468-2 - Metodologias de sínteses de nanoestruturas de dissulfeto de molibdênio (MoS2) e avaliação da sua potencial aplicação em sistemas de adsorção de poluentes
• Beneficiário: Rodrigo Schneider
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 17/12174-4 - Desenvolvimento de nanofibras poliméricas híbridas para aplicação na agricultura
• Beneficiário: Daniel Souza Corrêa
• Modalidade de apoio: Auxílio à Pesquisa - Regular