Sugar transporters from industrial fungi: Key to improving second-generation ethanol production

Autor(es)

Vieira Nogueira, Karoline Maria ^[1] ; Mendes, Vanessa ^[1] ; Carraro, Claudia Batista ^[1] ; Taveira, Iasmin Cartaxo ^[1] ; Oshiquiri, Leticia Harumi ^[1] ; Gupta, Vijai K. ^{[2, 3]} ; Silva, Roberto N. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Ribeirao Preto Med Sch FMRP, Dept Biochem & Immunol, Mol Biotechnol Lab, Ribeirao Preto, SP - Brazil

^[2] Mohammed VI Polytech Univ UM6P, AgroBiosci AgBS, Lot 660, Hay Moulay Rachid 43150, Benguerir - Morocco

^[3] Mohammed VI Polytech Univ UM6P, Chem & Biochem Sci CBS, Lot 660, Hay Moulay Rachid 43150, Benguerir - Morocco

• Tipo de documento: Artigo Científico
• Fonte: RENEWABLE & SUSTAINABLE ENERGY REVIEWS; v. 131, OCT 2020.
• Citações Web of Science: 6

Resumo

Second-generation ethanol (2G ethanol) has emerged as a promising alternative to fossil fuels owing to the usage of lignocellulosic biomass (LCB) as feedstock. LCB is mainly composed of cellulose, hemicellulose, and lignin. Biochemical conversion of LCB into ethanol involves four significant steps including pre-treatment, enzymatic hydrolysis, fermentation, and distillation. The major bottleneck to economically feasible 2G ethanol production lies in saccharification and fermentation steps. Lignocellulolytic fungi represent the major commercial sources of biomass-degrading carbohydrate-active enzymes (CAZymes) and possessa complex transporter system that is capable of effectively transporting thesugars released from holocellulosehydrolysates. In this context, an improved understanding of fungal sugar transporters can represent an important strategy to overcome the above-mentioned limitations. With this backdrop, the current paper reviews thesugar transporters from lignocellulolytic fungi, and their importance in 2G ethanol production. (AU)

• Processo FAPESP: 18/25898-3 - Engenharia genética e metabólica de uma linhagem industrial de Saccharomyces cerevisiae para o transporte e co-fermentação de xilose e celobiose visando aprimoramento do processo de produção de etanol a partir do bagaço de cana-de-açúcar
• Beneficiário: Karoline Maria Vieira Nogueira
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado