Light-based technologies for management of COVID-19 pandemic crisis

Autor(es)

Sabino, Caetano P. ^{[1, 2]} ; Ball, Anthony R. ^[3] ; Baptista, Mauricio S. ^[4] ; Dai, Tianhong ^{[5, 6]} ; Hamblin, Michael R. ^{[5, 7]} ; Ribeiro, Martha S. ^[8] ; Santos, Ana L. ^{[9, 3, 10]} ; Sellera, Fabio P. ^{[11, 12]} ; Tegos, George P. ^{[3, 13]} ; Wainwright, Mark ^[14]

Afiliação do(s) autor(es):Mostrar menos -

^[1] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Clin Anal, Sao Paulo, SP - Brazil

^[2] BioLambda Sci & Commercial LTD, Sao Paulo, SP - Brazil

^[3] GAMA Therapeut LLC, Massachusetts Biomed Initiatives, Worcester, MA - USA

^[4] Univ Sao Paulo, Inst Chem, Dept Biochem, Sao Paulo, SP - Brazil

^[5] Harvard Med Sch, Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02115 - USA

^[6] Harvard Med Sch, Massachusetts Gen Hosp, Vaccine & Immunotherapy Ctr, Boston, MA 02115 - USA

^[7] Univ Johannesburg, Fac Hlth Sci, Laser Res Ctr, Doornfontein - South Africa

^[8] Natl Commiss Nucl Energy, Ctr Lasers & Applicat, Nucl & Energy Res Inst, Sao Paulo, SP - Brazil

^[9] Rice Univ, Dept Chem, Houston, TX - USA

^[10] IdISBA Fdn Invest Sanitaria Islas Baleares, Palma De Mallorca - Spain

^[11] Univ Sao Paulo, Sch Vet Med & Anim Sci, Dept Internal Med, Sao Paulo, SP - Brazil

^[12] Univ Metropolitana Santos, Sch Vet Med, Santos, SP - Brazil

^[13] Micromoria LLC, Marlborough, MA - USA

^[14] Liverpool John Moores Univ, Sch Pharm & Biomol Sci, Liverpool, Merseyside - England

• Tipo de documento: Artigo de Revisão
• Fonte: JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY; v. 212, NOV 2020.
• Citações Web of Science: 11

Resumo

The global dissemination of the novel coronavirus disease (COVID-19) has accelerated the need for the implementation of effective antimicrobial strategies to target the causative agent SARS-CoV-2. Light-based technologies have a demonstrable broad range of activity over standard chemotherapeutic antimicrobials and conventional disinfectants, negligible emergence of resistance, and the capability to modulate the host immune response. This perspective article identifies the benefits, challenges, and pitfalls of repurposing light-based strategies to combat the emergence of COVID-19 pandemic. (AU)

• Processo FAPESP: 17/22406-0 - Desenvolvimento de equipamento inteligente para aplicação clínica de fototerapias com ajuste dosimétrico automático e pagamento sob demanda
• Beneficiário: Caetano Padial Sabino
• Modalidade de apoio: Auxílio à Pesquisa - Pesquisa Inovativa em Pequenas Empresas - PIPE
• Processo FAPESP: 13/07937-8 - Redoxoma
• Beneficiário: Ohara Augusto
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs