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(Referência obtida automaticamente do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Influence of environmental dust in transformation capacity of Streptococcus pneumoniae

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Autor(es):
José Diogo de Oliveira ; Carlos Fernando Macedo ; João Paulo de Oliveira Guarnieri ; Thaís Holtz Theizen ; Daisy Machado ; Marcelo Lancellotti
Número total de Autores: 6
Tipo de documento: Artigo Científico
Fonte: GENETICS AND MOLECULAR BIOLOGY; v. 44, n. 1, p. -, 2021.
Citações Web of Science: 0
Resumo

Abstract S. pneumoniae, commonly known as pneumococcus, is a naturally competent Gram-positive bacterium and is the major cause of pneumonia in elderly and children in developing countries. This pathogen is associated with respiratory diseases affected by pollution. The objective of this work was determining the effect of ash and environmental dust from the burning of sugarcane on pneumococci bacterial transformation. The transformation capacity of the Pn360 pneumococci strain was performed using the assays of DNA donor of mutant for luxS gene. Thus, the transformation tests were performed in contact with dust collected in the southwestern region of Brazil (important region where burning of sugar cane is present in the agriculture). The use of degradative practices in the sugar cane agriculture in Brazil was involved in the transformation capacity of the S. pneumoniae. This phenomenon includes important consequences for public health concerning to resistance acquisition and new virulence factors of this important infection. In conclusion, we obtained important results concerning the action of environmental pollution in Streptococcus pneumoniae transformation, increasing the DNA acquisition for this pathogen. (AU)

Processo FAPESP: 12/15046-3 - Estudo do genoma e metaboloma de linhagens de Haemophilus influenzae biótipo aegyptius causadores da febre púrpura brasileira
Beneficiário:Marcelo Lancellotti
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 11/14079-2 - Uso de nanopartículas em vacinas contra meningites bacterianas
Beneficiário:Marcelo Lancellotti
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 18/09874-7 - Análise e utilização do genoma de Haemophilus influenzae biotipo aegyptius para fins biotecnológicos
Beneficiário:Marcelo Lancellotti
Linha de fomento: Auxílio à Pesquisa - Regular