Substituted Naphthols: Preparations, Applications, and Reactions

Autor(es)

Mora Vargas, Jorge Andres ^{[1, 2]} ; Day, David P. ^[1] ; Burtoloso, Antonio C. B. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Quim Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil

^[2] Univ Santiago de Cali, Fac Ciencias Bas, Calle 5 62-00, Campus Pampalinda, Santiago De Cali - Colombia

• Tipo de documento: Artigo de Revisão
• Fonte: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; v. 2021, n. 5 NOV 2020.
• Citações Web of Science: 0

Resumo

Substituted naphthols (SNs) are an important class of chemical compounds present in many natural and synthetic products with biological and pharmaceutical activities. Moreover, the naphthol skeleton has been employed as a starting material for the development of drug molecules and natural products. Thus, different synthetic methods to access naphthol cores have been reported using diverse starting materials and chemical strategies. This review article describes literature on synthetic methodologies of substituted naphthols synthesized from alkynes, sulfur ylides, diazo substrates, alkenes/cyclopropenes, ketones/oxanorbenes/furans, amongst other key reactants. (AU)

• Processo FAPESP: 19/05002-8 - Investigando Transformações Enantiosseletivas de Diazocetonas e Ilídeos Sulfoxônios.
• Beneficiário: David Philip Day
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado