Effect of titanium tetrafluoride/sodium fluoride solutions containing chitosan at different viscosities on the protection of enamel erosion in vitro

Autor(es)

de Souza, Beatriz Martines ^[1] ; Pereira Santi, Larissa Rodrigues ^{[2, 1]} ; Joao-Souza, Samira Helena ^[2] ; Carvalho, Thiago Saads ^[2] ; Magalhaes, Ana Carolina ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Bauru Sch Dent, Dept Biol Sci, Alameda Octavio Pinheiro Brisolla 9-75, BR-17012191 Bauru, SP - Brazil

^[2] Univ Bern, Dept Restorat Prevent & Pediat Dent, Freiburgstr 7, CH-3010 Bern - Switzerland

• Tipo de documento: Artigo Científico
• Fonte: ARCHIVES OF ORAL BIOLOGY; v. 120, DEC 2020.
• Citações Web of Science: 0

Resumo

Objective: The aim of this in vitro study was to evaluate the protective effect against enamel erosion of experimental solutions containing TiF4/NaF and Chitosan compared to a commercial SnCl2/NaF/AmF solution. Design: Bovine enamel samples were divided (n = 15/group) into: (1) commercial solution SnCl2/NaF/AmF (500 ppm F-, positive control); (2) NaF/TiF4 (490 ppm F-); (3) similar to 2 plus 0.5 % chitosan (Ch) (500 mPas), (4) similar to 2 plus 0.5 % chitosan (2000 mPas), (5) negative control (water), (6) 0.5 % chitosan (500 mPas) and (7) 0.5 % chitosan (2000 mPas). The samples were submitted to a pH cycling (0.1 % citric acid, 4 x 90 s/day, interposed by artificial saliva) and daily treatment application (after the last erosive challenge, 1 x 30 s/day) for seven days. After the first day, the surface reflection intensity changes (% rSRI) were measured. After 7 days, the erosive enamel loss was quantified by contact profilometer. The % rSRI and the enamel loss (mu m) were compared using ANOVA/Tukey and Kruskal-Wallis/Dunn, respectively (p < 0.05). Results: The solution containing TiF4/NaF plus Ch 500 mPas was the only able to reduce the early erosive demineralization compared to negative control (p = 0.003). However, it did not differ from the other solutions. Enamel samples treated with SnCl2/NaF/AmF presented the lowest median loss value {[}0.72 (0.18) mu m] followed by both TiF4 + Ch {[}1.24 (0.49) and 1.28 (0.25)]; which significantly differed from the negative control {[}1.70 (0.27)]. Conclusion: The experimental solution containing TiF4/NaF plus chitosan (2000 mPas) has comparable effect to SnCl2/NaF/AmF on the protection against enamel erosion. (AU)

• Processo FAPESP: 16/24538-8 - Avaliação do efeito de soluções experimentais para bochecho compostas por NaF e TiF4 sobre a erosão e abrasão dentária in situ
• Beneficiário: Larissa Rodrigues Pereira Santi
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
• Processo FAPESP: 19/00778-8 - Efeito protetor das soluções de TiF4/NaF e quitosana sobre o desenvolvimento de erosão precoce do esmalte e no desgaste erosivo do esmalte in vitro
• Beneficiário: Larissa Rodrigues Pereira Santi
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Iniciação Científica