Vector-Focused Approaches to Curb Malaria Transmission in the Brazilian Amazon: An Overview of Current and Future Challenges and Strategies

Autor(es)

Rocha, Elerson Matos ^[1] ; Katak, Ricardo de Melo ^[1] ; de Oliveira, Juan Campos ^[1] ; Araujo, Maisa da Silva ^[2] ; Carlos, Bianca Cechetto ^{[3, 4]} ; Galizi, Roberto ^[5] ; Tripet, Frederic ^[5] ; Marinotti, Osvaldo ^[6] ; Souza-Neto, Jayme A. ^{[3, 4]}

Afiliação do(s) autor(es)

^[1] Univ Fed Amazonas PPGBIOTEC UFAM, Programa Posgrad Biotecnol, BR-69067005 Manaus, Amazonas - Brazil

^[2] FIOCRUZ RONDONIA, Lab Med Entomol, Oswaldo Cruz Fdn, BR-76812245 Porto Velho, RO - Brazil

^[3] Sao Paulo State Univ UNESP, Sch Agr Sci, Dept Bioproc & Biotechnol, BR-18610034 Botucatu, SP - Brazil

^[4] Sao Paulo State Univ UNESP, Sch Agr Sci, Cent Multiuser Lab, BR-18610034 Botucatu, SP - Brazil

^[5] Keele Univ, Ctr Appl Entomol & Parasitol, Sch Life Sci, Keele ST5 5GB, Staffs - England

^[6] MTEKPrime, Aliso Viejo, CA 92656 - USA

• Tipo de documento: Artigo de Revisão
• Fonte: TROPICAL MEDICINE AND INFECTIOUS DISEASE; v. 5, n. 4 DEC 2020.
• Citações Web of Science: 1

Resumo

In Brazil, malaria transmission is mostly confined to the Amazon, where substantial progress has been made towards disease control in the past decade. Vector control has been historically considered a fundamental part of the main malaria control programs implemented in Brazil. However, the conventional vector-control tools have been insufficient to control or eliminate local vector populations due to the complexity of the Amazonian rainforest environment and ecological features of malaria vector species in the Amazon, especially Anopheles darlingi. Malaria elimination in Brazil and worldwide eradication will require a combination of conventional and new approaches that takes into account the regional specificities of vector populations and malaria transmission dynamics. Here we present an overview on both conventional and novel promising vector-focused tools to curb malaria transmission in the Brazilian Amazon. If well designed and employed, vector-based approaches may improve the implementation of malaria-control programs, particularly in remote or difficult-to-access areas and in regions where existing interventions have been unable to eliminate disease transmission. However, much effort still has to be put into research expanding the knowledge of neotropical malaria vectors to set the steppingstones for the optimization of conventional and development of innovative vector-control tools. (AU)

• Processo FAPESP: 13/11343-6 - Caracterização dos mecanismos de ação anti-dengue mediados pela microbiota intestinal de populações naturais do mosquito Aedes aegypti
• Beneficiário: Jayme Augusto de Souza-Neto
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores