Transient Pulmonary Artery Hypertension in Holstein Neonate Calves

Autor(es)

Yasuoka, Melina Marie ^[1] ; Monteiro, Bruno Moura ^[2] ; Fantinato-Neto, Paulo ^[1] ; Paiano, Renan Braga ^[2] ; Fantoni, Denise Tabacchi ^[3] ; Otsuki, Denise Aya ^[4] ; Birgel Junior, Eduardo Harry ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Coll Anim Sci & Food Engn, Dept Vet Med, BR-13635900 Pirassununga - Brazil

^[2] Univ Sao Paulo, Sch Vet Med & Anim Sci, Dept Anim Reprod, BR-05508270 Sao Paulo - Brazil

^[3] Univ Sao Paulo, Fac Vet Med & Anim Sci, Dept Surg, BR-05508270 Sao Paulo - Brazil

^[4] Univ Sao Paulo, Sch Med, LIM 08, BR-01246000 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: ANIMALS; v. 10, n. 12 DEC 2020.
• Citações Web of Science: 0

Resumo

Simple Summary At birth, calves are challenged to maintain their vital functions that were previously supported by the placenta of cows. Failures in the neonatal adaptation process can occur during this and can cause the death of neonates. The present study aimed at the invasive hemodynamic evaluation of calves during the first 30 days of life to elucidate the changes in calves during this stage of life. In conclusion, the results of this research show a transient pulmonary arterial hypertension during the process of adapting to extrauterine life. The neonatal period is a challenging phase for calves, and during this phase constant adaptations are required. The aim of the present study was to evaluate the invasive hemodynamics with the Swan-Ganz catheter in neonate calves to understand adaptive changes during the first 30 days of life. A prospective and observational study was conducted with 10 Holstein calves. Assessments of the right atrial pressure (RAP), right ventricular pressure (RVP), pulmonary artery pressure (PAP), pulmonary capillary pressure (PW), cardiac output (CO), heart rate (HR), pulmonary vascular resistance (PVR), and blood gas levels were performed. The analyses of PAP, PVR, PW, HR, sO(2), and arterial blood gases differed (p < 0.05) between the evaluated periods. Our results indicated transient pulmonary artery hypertension during the process of extrauterine adaptation during the first 30 days of life. This hypertension must be considered as physiological and consequent to the neonatal adaptation process. (AU)

• Processo FAPESP: 10/08670-7 - Determinação dos valores da pressão da arteria pulmonar, da oximetria, da hemogasometria e dos teores plasmáticos de lactato em bezerros originados por meio da técnica de transferência nuclear de células somáticas adultas - Clonagem.
• Beneficiário: Eduardo Harry Birgel Junior
• Modalidade de apoio: Auxílio à Pesquisa - Regular