hedding Light on the Dynamic Role of the ``Target of Rapamycin{''} Kinase in the Fast-Growing C-4 Species Setaria viridis, a Suitable Model for Biomass Crop

Autor(es)

da Silva, Viviane Cristina Heinzen ^{[1, 2]} ; Martins, Marina C. M. ^{[3, 1]} ; Calderan-Rodrigues, Maria Juliana ^{[4, 1]} ; Artins, Anthony ^[4] ; Monte Bello, Carolina Cassano ^{[4, 1]} ; Gupta, Saurabh ^{[4, 5]} ; Sobreira, Tiago J. P. ^[6] ; Riano-Pachon, Diego Mauricio ^{[7, 1]} ; Mafra, Valeria ^[1] ; Caldana, Camila ^{[4, 1]}

Afiliação do(s) autor(es)

^[1] Natl Ctr Res Energy & Mat CNPEM, Campinas - Brazil

^[2] Univ Estadual Campinas UNICAMP, Ctr Biol Mol & Engn Genet CBMEG, Ctr Quim Med CQMED, Genom Climate Change Res Ctr GCCRC, Campinas - Brazil

^[3] Univ Sao Paulo, Inst Biociencias, Dept Bot, Lab Fisiol Ecol Plantas LAFIECO, Sao Paulo - Brazil

^[4] Max Planck Inst Mol Plant Physiol, Potsdam - Germany

^[5] Univ Potsdam, Inst Biochem & Biol, Potsdam - Germany

^[6] Purdue Univ, Bindley Biosci Ctr, W Lafayette, IN 47907 - USA

^[7] Univ Sao Paulo, Ctr Nucl Energy Agr, Piracicaba - Brazil

• Tipo de documento: Artigo Científico
• Fonte: FRONTIERS IN PLANT SCIENCE; v. 12, APR 13 2021.
• Citações Web of Science: 1

Resumo

The Target of Rapamycin (TOR) kinase pathway integrates energy and nutrient availability into metabolism promoting growth in eukaryotes. The overall higher efficiency on nutrient use translated into faster growth rates in C-4 grass plants led to the investigation of differential transcriptional and metabolic responses to short-term chemical TOR complex (TORC) suppression in the model Setaria viridis. In addition to previously described responses to TORC inhibition (i.e., general growth arrest, translational repression, and primary metabolism reprogramming) in Arabidopsis thaliana (C-3), the magnitude of changes was smaller in S. viridis, particularly regarding nutrient use efficiency and C allocation and partitioning that promote biosynthetic growth. Besides photosynthetic differences, S. viridis and A. thaliana present several specificities that classify them into distinct lineages, which also contribute to the observed alterations mediated by TOR. Indeed, cell wall metabolism seems to be distinctly regulated according to each cell wall type, as synthesis of non-pectic polysaccharides were affected in S. viridis, whilst assembly and structure in A. thaliana. Our results indicate that the metabolic network needed to achieve faster growth seems to be less stringently controlled by TORC in S. viridis. (AU)

• Processo FAPESP: 12/19561-0 - Regulação do crescimento pela via Target of rapamycin (TOR) em plantas
• Beneficiário: Camila Caldana
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOEN - Jovens Pesquisadores
• Processo FAPESP: 14/10407-3 - Interação entre a via Target of Rapamycin (TOR) e o metabolismo energético em plantas
• Beneficiário: Carolina Cassano Monte Bello
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 14/07918-6 - Caracterização funcional do gene Target of Rapamycin using Setaria como planta modelo: dissecando o papel da via TOR regulando crescimento e metabolismo em plantas C4
• Beneficiário: Valéria Mafra Cota
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado