| Texto completo | |
| Autor(es): |
Willis, Jace A.
[1]
;
Cheburkanov, Vsevolod
[1]
;
Kassab, Giulia
[2]
;
Soares, Jennifer M.
[2]
;
Blanco, Kate C.
[2]
;
Bagnato, Vanderlei S.
[2, 3]
;
Yakovlev, Vladislav V.
[1]
Número total de Autores: 7
|
| Afiliação do(s) autor(es): | [1] Texas A&M Univ, Dept Biomed Engn, College Stn, TX 77843 - USA
[2] Univ Sao Paulo, Sao Carlos Inst Phys, Sao Carlos, SP - Brazil
[3] Texas A&M Univ, Hagler Inst Adv Studies, College Stn, TX 77843 - USA
Número total de Afiliações: 3
|
| Tipo de documento: | Artigo de Revisão |
| Fonte: | APPLIED PHYSICS REVIEWS; v. 8, n. 2 JUN 2021. |
| Citações Web of Science: | 0 |
| Resumo | |
Antibiotic-resistant bacteria, which are growing at a frightening rate worldwide, has put the world on a long-standing alert. The COVID-19 health crisis reinforced the pressing need to address a fast-developing pandemic. To mitigate these health emergencies and prevent economic collapse, cheap, practical, and easily applicable infection control techniques are essential worldwide. Application of light in the form of photodynamic action on microorganisms and viruses has been growing and is now successfully applied in several areas. The efficacy of this approach has been demonstrated in the fight against viruses, prompting additional efforts to advance the technique, including safety use protocols. In particular, its application to suppress respiratory tract infections and to provide decontamination of fluids, such as blood plasma and others, can become an inexpensive alternative strategy in the fight against viral and bacterial infections. Diverse early treatment methods based on photodynamic action enable an accelerated response to emerging threats prior to the availability of preventative drugs. In this review, we evaluate a vast number of photodynamic demonstrations and first-principle proofs carried out on viral control, revealing its potential and encouraging its rapid development toward safe clinical practice. This review highlights the main research trends and, as a futuristic exercise, anticipates potential situations where photodynamic treatment can provide a readily available solution. (AU) | |
| Processo FAPESP: | 18/18188-0 - Inativação fotodinâmica da Pneumonia Bacteriana utilizando nebulização do fotossensibilizador e iluminação extracorpórea |
| Beneficiário: | Giulia Kassab |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 13/07276-1 - CEPOF - Centro de Pesquisa em Óptica e Fotônica |
| Beneficiário: | Vanderlei Salvador Bagnato |
| Modalidade de apoio: | Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs |
| Processo FAPESP: | 19/13569-8 - Estudo dos Mecanismos de Ação em Terapia Fotodinâmica: Do Fotossensibilizador à Aplicação Prática |
| Beneficiário: | Lucas Danilo Dias |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |