| Texto completo | |
| Autor(es): |
Pacheco Pinto, Roberto Damian
[1]
;
Abe, Ricardo Yuji
[1]
;
Gomes, Flavia Cid
[1]
;
Tagliari Barbisan, Paulo Rodolfo
[1]
;
Martini, Alexandre Fattah
[1]
;
Borges, Daniel de Almeida
[1]
;
Fernandes, Arthur Gustavo
[2]
;
Leite Arieta, Carlos Eduardo
[1]
;
Alves, Monica
[1]
Número total de Autores: 9
|
| Afiliação do(s) autor(es): | [1] Univ Estadual Campinas, Dept Ophthalmol & Otorhinolaryngol, Campinas, SP - Brazil
[2] Univ Fed Sao Paulo UNIFESP, Dept Oftalmol & Ciencias Visuais, Escola Paulista Med, Sao Paulo, SP - Brazil
Número total de Afiliações: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | SCIENTIFIC REPORTS; v. 11, n. 1 JUN 21 2021. |
| Citações Web of Science: | 0 |
| Resumo | |
To assess the quality of life of keratoconus patients using the Keratoconus Outcomes Research Questionnaire (KORQ), translated and validated in Portuguese language. The KORQ is the only validated keratoconus specific questionnaire and has a high rating for its psychometric properties. This cross-sectional study enrolled 100 keratoconus patients from a tertiary referral eye hospital between April 2018 and June 2019. Associations between age, sex, allergic conjunctivitis, keratoconus stage, best-corrected visual acuity (BCVA), maximum simulated keratometry (Kmax), steep keratometry (K2), pachymetry, treatments performed, hydrops, and KORQ scores were evaluated using univariate (Wilcoxon test and the Kruskal Wallis test) and multivariate linear regression with stepwise backward modeling. Lower KORQ scores are associated with better quality of life, whereas, higher scores are associated with greater impairment of functional activities and symptoms. Among the 100 patients, mild, moderate, and severe keratoconus were observed in 15%, 46% and 39% of participants, respectively. Univariate analysis showed lower function scores values, with male sex (p<0.05) and both functional and symptom scores were significantly associated with BCVA<0.3 (LogMAR) (p<0.05). Multivariate analysis indicated significantly lower functional scores in individuals with BCVA<0.3 (LogMAR) (p<0.001) and those with a history of crosslinking treatment (p=0.022), while symptom scores were only significantly associated with only BCVA<0.3 (LogMAR) (p<0.001). In patients with keratoconus, BCVA in the better eye and history of crosslinkig were factors associated with better quality of life scores using the KORQ. (AU) | |
| Processo FAPESP: | 14/19138-5 - Criação do biobanco de tecidos oculares e investigação de novos mecanismos fisiopatológicos relacionados a doenças oculares do segmento anterior |
| Beneficiário: | Mônica de Cássia Alves |
| Modalidade de apoio: | Auxílio à Pesquisa - Jovens Pesquisadores |