Drinking water nitrosamines in a large metropolitan region in Brazil

Autor(es)

Vizioli, Beatriz De Caroli ^[1] ; Hantao, Leandro Wang ^[1] ; Montagner, Cassiana Carolina ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Inst Chem, Dept Analyt Chem, BR-13083970 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Environmental Science and Pollution Research; v. 28, n. 25, p. 32823-32830, JUL 2021.
• Citações Web of Science: 0

Resumo

Nitrosamines are a concerning group of carcinogens, which have gained increasing attention over the last years, frequently found in drinking and recycled water systems. In this work, an analytical method was developed for the detection and quantification of seven nitrosamines (NDMA, NMEA, NPYR, NDEA, NPIP, NDPA, and NDBA) in drinking water. The method is based on gas chromatography coupled with a single quadrupole mass spectrometer (GC-MS) with electron ionization (EI) mode. Sample enrichment and matrix cleanup by solid-phase extraction (SPE) were performed using the US EPA Method 521 cartridge packed with coconut-based charcoal. The simple method allowed reliable identification and quantification of nitrosamines in the water at nanogram per liter levels. The optimized method was validated at three concentration levels (20, 100, and 200 ng L-1) in ultrapure and drinking water samples. Average recoveries were 63-87% for ultrapure water and 38-79% for drinking water with relative standard deviations (RSD) below 10% for both matrices. Method detection limits were 1.23-3.14 ng L-1. The described method was applied to eighteen drinking water samples collected from 13 cities of the Metropolitan Region of Campinas (Sao Paulo, Brazil). NDMA was the most frequent nitrosamine detected (89% of samples) and had the highest concentration level found (67 ng L-1). The levels of nitrosamines found in drinking water samples are of considerable relevance since the selected area is a major urban center that has amply expanded industrial and agricultural activities over the last few decades. To the best of our knowledge, this is the first evaluation of nitrosamines in drinking water conducted in Brazil to date. (AU)

• Processo FAPESP: 14/50951-4 - INCT 2014: Tecnologias Analíticas Avançadas
• Beneficiário: Celio Pasquini
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 14/24740-6 - Priorização de contaminantes aquáticos emergentes para o estado de São Paulo
• Beneficiário: Cassiana Carolina Montagner
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 17/25490-1 - Síntese e aplicação de líquidos iônicos no estudo de processos fermentativos de interesse comercial
• Beneficiário: Leandro Wang Hantao
• Modalidade de apoio: Auxílio à Pesquisa - Regular