| Texto completo | |
| Autor(es): |
Faria, Vinicius Silva
[1]
;
Pejon, Taciane Maria Melges
[1]
;
Gobatto, Claudio Alexandre
[2]
;
de Araujo, Gustavo Gomes
[1]
;
Cornachione, Anabelle Silva
[3]
;
Beck, Wladimir Rafael
[1]
Número total de Autores: 6
|
| Afiliação do(s) autor(es): | [1] Univ Fed Sao Carlos, Dept Physiol Sci, Lab Endocrine Physiol & Phys Exercise, BR-13565905 Sao Carlos, SP - Brazil
[2] Univ Estadual Campinas, Sch Appl Sci, Lab Appl Sport Physiol, BR-13484350 Limeira, SP - Brazil
[3] Univ Fed Sao Carlos, Dept Physiol Sci, Muscle Physiol & Biophys Lab, BR-13565905 Sao Carlos, SP - Brazil
Número total de Afiliações: 3
|
| Tipo de documento: | Artigo Científico |
| Fonte: | SCIENTIFIC REPORTS; v. 11, n. 1 SEP 28 2021. |
| Citações Web of Science: | 0 |
| Resumo | |
The present study investigated the effects of acute melatonin administration on the biomarkers of energy substrates, GLUT4, and FAT/CD36 of skeletal muscle and its performance in rats subjected to exhaustive swimming exercise at an intensity corresponding to the maximal aerobic capacity (tlim). The incremental test was performed to individually determine the exercise intensity prescription and 48 h after, the animals received melatonin (10 mg center dot kg(-1)) or vehicles 30 min prior to tlim. Afterwards, the animals were euthanized 1 or 3 h after the exhaustion for blood and muscles storage. The experiment 1 found that melatonin increased the content of glycogen and GLUT4 in skeletal muscles of the animals that were euthanized 1 (p < 0.05; 22.33% and 41.87%) and 3 h (p < 0.05; 37.62% and 57.87%) after the last procedures. In experiment 2, melatonin enhanced the tlim (p = 0.01; 49.42%), the glycogen content (p < 0.05; 40.03%), GLUT4 and FAT/CD36 in exercised skeletal muscles (F = 26.83 and F = 25.28, p < 0.01). In summary, melatonin increased energy substrate availability prior to exercise, improved the exercise tolerance, and accelerated the recovery of muscle energy substrates after the tlim, possibly through GLUT4 and FAT/CD36. (AU) | |
| Processo FAPESP: | 19/08148-3 - Melatonina e performance física: da ergogenia à aceleração do reparo músculo esquelético pós dano induzido por exercício físico |
| Beneficiário: | Wladimir Rafael Beck |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |