Expulsion and continuation rates of the levonorgestrel 52 mg intrauterine system was similar among nulligravid and parous users

Autor(es)

Brull, Eliza ^[1] ; Machado, Helymar Costa ^[1] ; Bahamondes, Luis ^[1] ; Juliato, Cassia R. T. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Campinas UNICAMP, Fac Med Sci, Dept Obstet & Gynecol, Rua Alexander Fleming 101, Cidade Univ Zeferino Va, BR-13083881 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: International Journal of Gynecology & Obstetrics; NOV 2021.
• Citações Web of Science: 0

Resumo

Objective To compare the expulsion and continuation rates of the levonorgestrel (LNG) 52 mg intrauterine system (IUS) in a cohort of nulligravid and parous users. Methods We conducted a retrospective cohort study that included 996 participants in whom we placed an LNG-IUS, and the participants were monitored for up to 5 years after device placement. We identify 498 nulligravid participants in the medical record database between 2012 and 2020. Each nulligravida was paired with a parous users who had an LNG-IUS inserted on the same day, just before or after the nulligravida. The Kaplan-Meier method and the log-rank test were used to compare the survival curves of the two groups. Results By the fifth year of use, the expulsion rates were 7.6/100 and 8.2/100 women-years (W-Ys) and the continuation rates were 641/100 W-Ys and 65.4/100 W-Ys without difference among nulligravid and parous users, respectively (P = 0.782 and P = 0.564, respectively). We observed 29 and 31 expulsions among nulligravid and parous users, respectively. Conclusion Nulligravid and parous participants who used the 52 mg LNG-IUS showed similar expulsion and continuation rates during five years of use. (AU)

• Processo FAPESP: 15/20504-9 - Manifestações clínicas de usuárias de contraceptivos de somente progestogênios
• Beneficiário: Luis Guillermo Bahamondes
• Modalidade de apoio: Auxílio à Pesquisa - Temático