In situ evaluation of desensitizing toothpastes for protecting against erosive tooth wear and its characterization

Autor(es)

Marianna Lopes, Raquel ^[1] ; Scaramucci, T. ^[1] ; Walker, Clandler L. ^[2] ; Feitosa, S. A. ^[2] ; Aranha, Ana Cecilia Correa ^{[1, 3]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Dent, Dept Restorat Dent, Ave Prof Lineu Prestes, 2227 Cidade Univ, BR-05508000 Sao Paulo, SP - Brazil

^[2] Indiana Univ, Sch Dent, Dept Biomed Sci & Comprehens Care, 1121 Michigan St, Indianapolis, IN 46202 - USA

^[3] Univ Sao Paulo, Special Lab Lasers Dent LELO, Sch Dent, Ave Prof Lineu Prestes, 2226 Cidade Univ, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: CLINICAL ORAL INVESTIGATIONS; v. 25, n. 12, p. 6857-6870, DEC 2021.
• Citações Web of Science: 0

Resumo

Objective This five-phase, single-blind, crossover in situ trial evaluated the effects of desensitizing or anti-erosive toothpastes on dentin erosive wear and tubule occlusion. Materials and methods Some characteristics such as relative dentin abrasivity (RDA), viscosity (V), cytotoxicity, and fluoride and calcium (Ca) availability of the toothpastes were also tested. Samples were positioned on removable intraoral appliances from 15 volunteers (n=4), according to the groups, C-control (0 ppm fluoride), F-sodium monofluorophosphate (MFP), A-MFP and arginine+calcium carbonate, CSP-calcium sodium phosphosilicate, and CS-MFP and calcium silicate+sodium phosphate. Erosion-abrasion cycling was performed (1% citric acid, 2min, 6x/day; toothbrushing, 5s, 2x/day). Surface loss (SL) was evaluated by optical profilometry. Environmental scanning electron microscopy images (ESEM) counted the number of open dentin tubules (ODTs). Data were statistically analyzed (alpha=0.05). Results There were no significant differences in SL among groups (p=0.468). The ODT for CSP, CS, and A groups were significantly lower than the control. CSP and CS presented significantly less ODT than F, but they did not significantly differ from A. F and CS were more abrasive than all the other toothpastes; CSP was more abrasive than A, and C was the least abrasive. CSP presented higher V (p<0.05). All toothpastes presented lower cell viability than the control without toothpaste exposure. F and A presented significantly higher values of F- (p<0.05). All fluoride toothpastes had similar amount of Ca, differing from the control (p<0.05). Conclusion Although the toothpastes caused similar degree of erosive wear, CSP and CS were able to occlude the dentin tubules. (AU)

• Processo FAPESP: 15/15629-7 - Análise da perda de estrutura dentinária e oclusão tubular após desafio erosivo e abrasivo com diferentes cremes dentais contendo agentes dessensibilizantes: estudo randomizado in situ
• Beneficiário: Raquel Marianna Lopes Gaona
• Modalidade de apoio: Bolsas no Brasil - Doutorado