Autor(es)

Maronezi, Marjury Cristina ; Carneiro, Rafael Kretzer ; da Cruz, Igor Cezar Kniphoff ; de Oliveira, Ana Paula Luiz ; De Nardi, Andrigo Barboza ; Pavan, Leticia ; Del'Aguila-Silva, Priscila ; Uscategui, Ricardo Andres Ramirez ; Feliciano, Marcus Antonio Rossi

• Tipo de documento: Artigo Científico
• Fonte: SCIENTIFIC REPORTS; v. 12, n. 1, p. 7-pg., 2022-03-11.

Resumo

The objective was to evaluate the accuracy of B-mode ultrasonography and ARFI elastography in detecting malignancy in canine splenic lesions. Thirty-seven spleens with abnormalities (16 benign and 21 malignant) from dogs of different breeds and ages were evaluated. Echogenicity, echotexture, organ length and height were evaluated using B-mode. By ARFI elastography, tissue stiffness was evaluated qualitatively (elastogram) and quantitatively (measuring the shear wave velocity-SWV). Lesions were classified as diffuse, focal or multifocal (cranial, medial or caudal portion) and comparisons of the SWV between the injured and non-injured areas were performed. In the B-mode, no features were associated to malignancy (P > 0.05). In the elastogram, 35 spleens were non-deformable and 2 deformable, having no association with malignancy. The greater SWV was observed in malignant lesions (3.4 +/- 0.6 m/s), followed by areas free from alterations (2.1 +/- 0.3 m/s) and benign lesions (1.7 +/- 0.5 m/s), with difference between groups (P < 0.0001). It was found that a SWV > 2.6 m/s indicates malignancy of canine splenic lesions (sensitivity of 95%, specificity of 100%, PPV of 100%, NPV of 94% and accuracy of 97%), concluding that ARFI elastography is a promising technique for differentiating malignancy in these lesions. (AU)

• Processo FAPESP: 17/14957-6 - Estudo de novas biotécnicas para reprodução de caninos e pequenos ruminantes
• Beneficiário: Wilter Ricardo Russiano Vicente
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 19/15282-8 - EMU concedido no processo 17/14957-6: Siemens S2000
• Beneficiário: Wilter Ricardo Russiano Vicente
• Modalidade de apoio: Auxílio à Pesquisa - Programa Equipamentos Multiusuários