| Texto completo | |
| Autor(es): |
Ribeiro, Adriana Barbosa
;
Ribeiro, Aline Barbosa
;
de Araujo, Camila Borba
;
Fortes, Caroline Vieira
;
Clemente, Lorena Mosconi
;
Oliveira Paranhos, Helena de Freitas
;
Watanabe, Evandro
;
Salgado, Helio Cesar
;
Silva-Lovato, Claudia Helena
Número total de Autores: 9
|
| Tipo de documento: | Artigo Científico |
| Fonte: | ANTIBIOTICS-BASEL; v. 11, n. 10, p. 13-pg., 2022-10-01. |
| Resumo | |
Denture-related stomatitis (DRS) is frequent oral inflammation in complete denture wearers. This study evaluated the effect of a hygiene protocol on DRS remission, local inflammatory factors, and hemodynamic responses. Thirty-three individuals were enrolled in the study. The outcomes were measured before and after 10 days of a hygiene protocol treatment consisting of brushing the palate with a soft brush and water and denture brushing with a denture-specific brush and mild soap, as well as immersion of the denture for 20 min in a 0.25% sodium hypochlorite solution. Data were analyzed by paired Wilcoxon for biofilm removal and CFU count of microorganisms. The paired T test was used to assess salivary MUC 1, cytokines, and arterial pressure (p < 0.05). A significant difference was found in the DRS degree (p < 0.001), biofilm (p < 0.001), microbial load of Candida spp. (p < 0.001), Gram-negative (p < 0.004), Staphylococcus spp. (p < 0.001), and S. mutans (p < 0.001) of the denture, and S. mutans (p < 0.001) of the palate after use of the protocol. The salivary flow (p = 0.2) and pH (p = 0.97) did not change; there was an increase of MUC 1 (p = 0.049) and a decrease in IL-6 (p = 0.038), IL-2 (p = 0.04), IL-10 (p = 0.041), and IFN gamma (p = 0.04). There was also a decrease in systolic (p = 0.012) and mean arterial pressure (p = 0.02). The current hygiene protocol reduced the inflammation degree of DRS and promoted an improvement of local inflammatory factors and a reduction in the systolic arterial pressure of the patients. (AU) | |
| Processo FAPESP: | 20/06043-7 - Modulação autonômica (simpática e parassimpática) das respostas inflamatórias e cardiocirculatórias em situações fisiopatológicas clínicas e experimentais |
| Beneficiário: | Helio Cesar Salgado |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 21/06988-4 - Relação da Estomatite Relacionada à Prótese (ERP) com risco cardiovascular e efeito da desinfecção de prótese comparada ao tratamento local na remissão da ERP e risco cardíaco: estudo clínico controlado, aleatorizado e duplo-cego |
| Beneficiário: | Adriana Barbosa Ribeiro |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |