| Texto completo | |
| Autor(es): |
Fleury, Eduardo
;
Marcomini, Karem
Número total de Autores: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | EUROPEAN RADIOLOGY EXPERIMENTAL; v. 3, n. 1, p. 8-pg., 2019-08-05. |
| Resumo | |
Background The purpose of this work was to evaluate computable Breast Imaging Reporting and Data System (BI-RADS) radiomic features to classify breast masses on ultrasound B-mode images. Methods The database consisted of 206 consecutive lesions (144 benign and 62 malignant) proved by percutaneous biopsy in a prospective study approved by the local ethical committee. A radiologist manually delineated the contour of the lesions on greyscale images. We extracted the main ten radiomic features based on the BI-RADS lexicon and classified the lesions as benign or malignant using a bottom-up approach for five machine learning (ML) methods: multilayer perceptron (MLP), decision tree (DT), linear discriminant analysis (LDA), random forest (RF), and support vector machine (SVM). We performed a 10-fold cross validation for training and testing of all classifiers. Receiver operating characteristic (ROC) analysis was used for providing the area under the curve with 95% confidence intervals (CI). Results The classifier with the highest AUC at ROC analysis was SVM (AUC = 0.840, 95% CI 0.6667-0.9762), with 71.4% sensitivity (95% CI 0.6479-0.8616) and 76.9% specificity (95% CI 0.6148-0.8228). The best AUC for each method was 0.744 (95% CI 0.677-0.774) for DT, 0.818 (95% CI 0.6667-0.9444) for LDA, 0.811 (95% CI 0.710-0.892) for RF, and 0.806 (95% CI 0.677-0.839) for MLP. Lesion margin and orientation were the optimal features for all the machine learning methods. Conclusions ML can aid the distinction between benign and malignant breast lesion on ultrasound images using quantified BI-RADS descriptors. SVM provided the highest ROC-AUC (0.840). (AU) | |
| Processo FAPESP: | 12/24006-5 - Caracterização de nódulos mamários em imagens digitais de ultrassonografia, elastografia e mamografia utilizando técnicas inteligentes |
| Beneficiário: | Karem Daiane Marcomini |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |