Busca avançada
Ano de início
Entree


Tracking the emergence of disparities in the subnational spread of COVID-19 in Brazil using an online application for real-time data visualisation: A longitudinal analysis

Texto completo
Autor(es):
Mostrar menos -
Mee, Paul ; Alexander, Neal ; Mayaud, Philippe ; Gonzalez, Felipe de Jesus Colon ; Abbott, Sam ; Santos, Andreza Aruska de Souza ; Acosta, Andre Luis ; Parag, Kris, V ; Pereira, Rafael H. M. ; Prete Jr, Carlos A. ; Sabino, Ester C. ; Faria, Nuno R. ; Brady, Oliver J. ; LSHTM Ctr Math Modelling Infect Di
Número total de Autores: 14
Tipo de documento: Artigo Científico
Fonte: LANCET REGIONAL HEALTH-AMERICAS; v. 5, p. 14-pg., 2022-01-21.
Resumo

Background Brazil is one of the countries worst affected by the COVID-19 pandemic with over 20 million cases and 557,000 deaths reported by August 2021. Comparison of real-time local COVID-19 data between areas is essential for understanding transmission, measuring the effects of interventions, and predicting the course of the epidemic, but are often challenging due to different population sizes and structures. Methods We describe the development of a new app for the real-time visualisation of COVID-19 data in Brazil at the municipality level. In the CLIC-Brazil app, daily updates of case and death data are downloaded, age standardised and used to estimate the effective reproduction number (Rt). We show how such platforms can perform real-time regression analyses to identify factors associated with the rate of initial spread and early reproduction number. We also use survival methods to predict the likelihood of occurrence of a new peak of COVID-19 incidence. Findings After an initial introduction in Sao Paulo and Rio de Janeiro states in early March 2020, the epidemic spread to northern states and then to highly populated coastal regions and the Central-West. Municipalities with higher metrics of social development experienced earlier arrival of COVID-19 (decrease of 11 center dot 1 days [95% CI:8.9,13.2] in the time to arrival for each 10% increase in the social development index). Differences in the initial epidemic intensity (mean R-t) were largely driven by geographic location and the date of local onset. Interpretation This study demonstrates that platforms that monitor, standardise and analyse the epidemiological data at a local level can give useful real-time insights into outbreak dynamics that can be used to better adapt responses to the current and future pandemics. Copyright (c) 2021 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) (AU)

Processo FAPESP: 18/14389-0 - Centro Conjunto Brasil-Reino Unido para Descoberta, Diagnóstico, Genômica e Epidemiologia de Arbovírus (CADDE)
Beneficiário:Ester Cerdeira Sabino
Modalidade de apoio: Auxílio à Pesquisa - Temático