| Texto completo | |
| Autor(es): |
Concepcion, Odette
;
Penaloza, Francisco J.
;
Lopez, Jhon Jairo
;
Cabrera-Barjas, Gustavo
;
Jimenez, Claudio A.
;
Paixao, Marcio W.
;
de la Torre, Alexander F.
Número total de Autores: 7
|
| Tipo de documento: | Artigo Científico |
| Fonte: | NEW JOURNAL OF CHEMISTRY; v. 46, n. 24, p. 8-pg., 2022-05-12. |
| Resumo | |
This work renders operational simplicity under mild conditions to synthesize some N-alkylated peptides and depsipeptides containing olefins. A sequential one-pot protocol merging a multicomponent reaction with oxidative elimination of phenylselenoxide allows the formation of alpha,beta and beta,gamma olefin containing peptides and depsipeptides. Consequently, the regioselective construction of alpha,beta-dehydrobutyrine and alpha,beta-dehydro-homophenylalanine was possible using the Ugi four-component reaction; meanwhile, the Passerini three-component reaction produces the beta-enamide preferably. (AU) | |
| Processo FAPESP: | 21/06099-5 - Desenvolvimento de novas metodologias fotoquímicas para síntese de pequenas moléculas e modificações de biomoléculas |
| Beneficiário: | Márcio Weber Paixão |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |