Silver nanoparticle incorporation into flexible polyamide 12 membranes

Autor(es)

Martins de Souza, Maria Gabriela ; Batista, Jessica Potomatti ; de Faria, Emerson Henrique ; Ciuffi, Katia Jorge ; Rocha, Lucas Alonso ; Nassar, Eduardo Jose ; Lopes da Silva, Jorge Vicente ; Oliveira, Marcelo Fernandes ; Maia, Izaque Alves

• Tipo de documento: Artigo Científico
• Fonte: Journal of Sol-Gel Science and Technology; v. 102, n. 1, p. 10-pg., 2022-01-20.

Resumo

To meet the demands of the market and society, the development of structured polymeric materials for application in the medical field is constantly increasing. Over the last decades, metallic silver nanoparticles have been explored due to their antimicrobial action. Here, we aimed to incorporate metallic silver nanoparticles into polymeric pieces obtained by additive manufacture via a chemical route involving silver nitrate and sodium borohydride. Polyamide 12 membranes were obtained by selective laser sintering, which was followed by washing, pretreatment, and functionalization with the alkoxides tetraethylorthosilicate and 3-aminopropyl tetraethoxysilane. For nanoparticle preparation and incorporation, a chemical route was tested under different conditions. The samples were characterized by techniques, such as X-ray diffraction, ultravioletvisible spectroscopy, and infrared vibrational spectroscopy. Nanoparticle formation and incorporation into the polyamide 12 membranes were demonstrated by the absorbance band at 420 nm, which indicated that the particles measured between 10 and 50 nm in size; by the X-ray diffraction peaks at 20 = 38, 44, and 64 degrees, which are typical of crystalline silver; and by vibrational spectroscopy, which evidenced that the nanoparticles interacted with the polyamide 12 nitrogen groups. Polyamide 12 membranes containing metallic silver nanoparticles have promising biomedical applications as antimicrobial wound dressings associated with drug carriers. [GRAPHICS] . (AU)

• Processo FAPESP: 19/02641-0 - 6th Nano Today Conference
• Beneficiário: Eduardo José Nassar
• Modalidade de apoio: Auxílio à Pesquisa - Reunião - Exterior
• Processo FAPESP: 19/26439-5 - Nanopartículas obtidas via sol-gel contendo íons lantanídeos para aplicação multimodal em Medicina
• Beneficiário: Eduardo José Nassar
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 15/20298-0 - Obtenção de matrizes luminescentes de LaNbO4:Ln (Ln = Dy, TM, er e Yb) pelo processo de pirólise de aerossol
• Beneficiário: Lucas Alonso Rocha
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 19/20214-1 - Incorporação de nanopartículas de prata e fármaco em membranas flexíveis de poliamida 12
• Beneficiário: Maria Gabriela Martins de Souza
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica