Resin-based materials to control human dentin permeability under erosive conditions in vitro: A hydraulic conductance, confocal microscopy and FTIR study

Autor(es)

Mosquim, Victor ; Caracho, Rafaela Aparecida ; Zabeu, Giovanna Speranza ; Condi, Luiza da Silveira ; Foratori-Junior, Gerson Aparecido ; Borges, Ana Flavia Sanches ; Wang, Linda

• Tipo de documento: Artigo Científico
• Fonte: Dental Materials; v. 38, n. 10, p. 10-pg., 2022-10-01.

Resumo

Objectives: To characterize the behavior of three different polymeric agents before and after an erosive challenge on dentin permeability, to analyze their degradation in both conditions, and to analyze their degree of conversion (DC).Methods: The permeability of human dentin disks (1.0 +/- 0.2 mm) was measured with smear layer, after its removal, after treatment (LpTreat) with Gluma Desensitizer, PRG Barrier Coat (PBC) or Icon infiltrant (n = 11/group) and after exposure to citric acid (LpEro) (6%, pH 2.1, 1 min). The specimens were analyzed under a Laser Scanning Confocal Microscope (n = 2/group) and the products' DC were calculated. Data were subjected to 2 -way repeated measures ANOVA and post-hoc Bonferroni (permeability analysis), to paired t-test (for specimens treated with Icon) and to t-test (DC analysis) (alpha < 0.05). Results: Icon showed the lowest LpTreat and LpEro values, while PBC and Gluma did not differ from each other under these conditions. Icon and PBC showed LpEro similar to a dentin with smear layer. Under the Laser Scanning Confocal Microscope, more deposits were noticeable on dentin after treating with PBC. Gluma presented the deepest penetra-tion in dentin. The DC of PBC was the highest. Significance: Icon caused the highest reduction on permeability values, followed by PBC and Gluma. PBC generated more deposits covering dentin and seemed to be more efficient after an erosive challenge. The association of a polymeric resin with inorganic ion-releasing fillers seem to be a great strategy to manage dentin hypersensitivity under erosive con-ditions.(c) 2022 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved. (AU)

• Processo FAPESP: 19/21128-1 - O papel dos agentes bioativos, resinosos e fluoretados no tratamento da hipersensibilidade dentinária e sua interação com a dentina hígida e erodida: estudos in vitro e clínico
• Beneficiário: Victor Mosquim
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 19/20970-0 - Análise físico-química da interação da dentina humana normal, irradiada e erodida artificialmente a monômeros resinosos funcionais
• Beneficiário: Linda Wang
• Modalidade de apoio: Auxílio à Pesquisa - Regular