Advances in the Transition Metal Catalyzed Carboxylation of Aryl Electrophiles: a Field Full of Opportunities for the Brazilian Chemical Society

Autor(es)

Batista, Gabriel M. F. ; de Castro, Pedro P.

• Tipo de documento: Artigo Científico
• Fonte: REVISTA VIRTUAL DE QUIMICA; v. N/A, p. 18-pg., 2023-02-08.

Resumo

Currently, the world faces a climate change that is correlated with CO2 emissions by humankind, thus scientists from different fields are constantly working on methods to use or capture this released CO2. Carbon dioxide is the holy grail for a C1 building block due to its high abundance, low cost and reduced toxicity. Enlighted by this, several groups have reported catalytic procedures to convert aryl electrophiles into the corresponding carboxylic acids. A general overview of these procedures will be covered, detailing each methodologATIN SMALL LETTER Y WITH ACUTEs main advantages and limitations. Finally, the main opportunities for further innovation in this field will be listed and discussed. (AU)

• Processo FAPESP: 21/13924-2 - Desenvolvimento de novas abordagens para síntese dos Insumos Farmacêuticos Ativos (IFAs) em regime de fluxo contínuo: Axitinibe, Lacosamida, Pioglitazona e Rosiglitazona
• Beneficiário: Pedro Pôssa de Castro
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado