Mechanochemical method: a powerful tool to obtain omega-poly(ethylene glycol)-functionalized structures and curcumin analogues

Autor(es)

de Moura, Aniele ; Gaglieri, Caroline ; Terciotti, Luiz Octavio ; Rinaldo, Daniel ; Caires, Flavio Junior

• Tipo de documento: Artigo Científico
• Fonte: NEW JOURNAL OF CHEMISTRY; v. 47, n. 19, p. 9-pg., 2023-04-18.

Resumo

This work reports the mechanochemical synthesis of organic compounds involving carbon-carbon (C-C), carbon-nitrogen (C-N), and carbon-oxygen (C-O). The solid-state synthesis of omega-poly(ethylene glycols) functionalized with different cyclic anhydrides and the obtainment of curcumin Schiff bases and curcumin multicomponent derivatives are also reported. The mechanochemical method was also used in the Steglich esterification using curcumin derivatives. H-1 NMR, C-13 NMR, MIR, XRPD, and HPLC techniques were performed to confirm the synthesis of each compound. (AU)

• Processo FAPESP: 18/24378-6 - Síntese, caracterização e estudo termoanalítico de cocristais de Valsartana, Candesartana Cilexetila e Olmesartana medoxomila
• Beneficiário: Flávio Junior Caires
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 13/07296-2 - CDMF - Centro de Desenvolvimento de Materiais Funcionais
• Beneficiário: Elson Longo da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs