Development of multifunctional sunscreens: Evaluation of physico-mechanical and film-forming properties

Autor(es)

Kakuda, Leticia ; Campos, Patricia Maria Berardo Goncalves Maia ; Zanin, Rafaela Bordini ; Favaro, Laura Noronha

• Tipo de documento: Artigo Científico
• Fonte: International Journal of Pharmaceutics; v. 635, p. 12-pg., 2023-02-20.

Resumo

The exposome consists of several factors such as solar radiation and pollution, which can provoke skin damage and lead to premature skin aging. Thus, the use of multifunctional sunscreens is critical in order to prevent this damage. In addition, film formation is very important to reach the expected SPF. Within this context, the objective of the present study was to develop and evaluate the in vivo SPF, sensory, physico-mechanical, and filmforming properties of sunscreens containing a biopolymer from Tara and red algae. A clinical study of the filmforming effect and of skin hydration was performed by instrumental measurements and by biophysical and skin imaging techniques. The SPF of both formulations, with or without the biopolymer, was 45.6. This result was 10.09% higher than expected. higher than expected. However, the sunscreen added to the biopolymer showed better sensory and texture properties, significantly increased skin hydration and reduced transepidermal water loss. The film-forming property was observed by the analysis of Reflectance Confocal Microscopy images 2, 4, and 6 h after formulation application, and this result was more pronounced for the sunscreen added to the biopolymer. Thus, the film-forming property of the biopolymer was important for prolonging the skin barrier function due to film formation and to obtain more effective and multifunctional sunscreens that provide longer protection. (AU)

• Processo FAPESP: 21/11000-8 - Desenvolvimento e avaliação da eficácia de formulações cosméticas contendo óleo de Pequi encapsulado em sistemas nanoestruturados
• Beneficiário: Letícia Kakuda
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 22/00897-0 - Desenvolvimento de formulações fotoprotetoras multifuncionais para a proteção e tratamento da pele e cabelos contra os efeitos do expossoma
• Beneficiário: Patrícia Maria Berardo Gonçalves Maia Campos
• Modalidade de apoio: Auxílio à Pesquisa - Regular