Efficacy of sodium hypochlorite combined with chlorhexidine against Enterococcus faecalis in vitro

Autor(es)

Vianna, Morgana E. ; Gomes, Brenda P. F. A.

• Tipo de documento: Artigo Científico
• Fonte: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology; v. 107, n. 4, p. 5-pg., 2009-04-01.

Resumo

The aim of this study was to investigate in vitro the efficacy of the combination of sodium hypochlorite (NaOCl) and chlorhexidine (CHX) in different concentrations against Enterococcus faecalis compard with the antimicrobial activity of the same irrigating substances when applied alone. The substances tested were 2.0% CHX gel, 2.0% CHX liquid, 1% NaOCl, 2.5% NaOCl, 5.25% NaOCl, and combinations of them in the same proportions. Two methods were used: the agar diffusion test and the broth dilution test. The largest mean microbial growth zone was obtained by 2.0% CHX gel, and the smallest zones were obtained by 1% and 2.5% NaOCl (P < .05). 2.0% CHX (gel and liquid formulation), 5.25% NaOCl, and the combination of 2.0% CHX liquid and 5.25% NaOCl, all of which needed <= 1 min to eliminate E. faecalis. The association of NaOCl and CHX did not improve the antimicrobial activity of CHX alone. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 107: 585-589) (AU)

• Processo FAPESP: 07/58518-4 - Análise da microbiota de canais radiculares de dentes humanos infectados através da cultura, clonagem e sequenciamento do gene 16S rRNA
• Beneficiário: Brenda Paula Figueiredo de Almeida Gomes
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 05/55695-7 - Suscetibilidade e identificacao bacteriana in vivo de patogenos encontrados em bolsas periodontais e canais radiculares frente a diferentes medicacoes intracanais.
• Beneficiário: Brenda Paula Figueiredo de Almeida Gomes
• Modalidade de apoio: Auxílio à Pesquisa - Regular