Dietary Levamisole Influenced Hematological Parameters of Juvenile Pacu, Piaractus mesopotamicus (Holmberg 1887)

Autor(es)

Sado, Ricardo Yuji ; de Almeida Bicudo, Alvaro Jose ; Possebon Cyrino, Jose Eurico

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF THE WORLD AQUACULTURE SOCIETY; v. 41, p. 10-pg., 2010-02-01.

Resumo

Diseases outbreaks are a major concern in intensive fish farming because fish are exposed to stressors which may negatively affect their physiology. This study set out to determine effects of dietary levamisole (Levamisole HCl; SIGMA (R)) on performance and hematology of pacu, Piaractus mesopotamicus, juveniles. Fish (55.94 g) were stocked into 24 plastic aquaria (500 L; 15 fish per aquarium) and fed for 30 d with a commercial diet with 0, 50, 100, 200, 400, and 800 mg/kg levamisole, and for an extra 15 d, with a control diet in a totally randomized design trial (n = 4). Biometrical and hematological data were collected. No significant differences in growth parameters were recorded for either control or supplemented diets. Hematological parameters, such as hemoglobin, plasma glucose, white blood count (WBC), and differential leukocyte count were influenced (P < 0.05) levamisole. WBC, lymphocytes, neutrophils, monocytes, eosinophils, and special granulocytic cell numbers decreased significantly after 15 d. Dietary levamisole at 100 mg/kg diet for 15 d increased leukocyte production in juvenile pacu. However, levamisole administration for more than 15 d presented toxicity to lymphopoietic tissues. Information about long-period administration, mode of action in weight gain, effects on hematology of levamisole in freshwater fish nutrition are scarce and necessary for its safe use in aquaculture. (AU)

• Processo FAPESP: 05/51967-2 - Estudo "in vivo" da eficacia na utilizacao de imunoestimulante na dieta de juvenis de "pseudoplatystoma corruscans" (spix & agassiz, (spix & agassiz, 1829) respostas biologicas, bioquimicas e hematolo
• Beneficiário: Ricardo Yuji Sado
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 05/51968-9 - Exigencias nutricionais em energia, proteina e aminoacidos de pacu (piaractus mesopotamicus holmberg 1887).
• Beneficiário: Alvaro Jose de Almeida Bicudo
• Modalidade de apoio: Bolsas no Brasil - Doutorado