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Effects of surface treatments on Y-TZP phase stability, microstructure and osteoblast cell response

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Autor(es):
Bruni, Yesica L. ; Garrido, Liliana B. ; Albano, Maria P. ; Teixeira, Lucas Novaes ; Rosa, Adalberto Luiz ; de Oliveira, Paulo Tambasco
Número total de Autores: 6
Tipo de documento: Artigo Científico
Fonte: CERAMICS INTERNATIONAL; v. 41, n. 10, p. 11-pg., 2015-12-01.
Resumo

The effects of hydrothermal and phosphoric acid treatments on the tetragonal ZrO2 stability and surface microstructure were determined for 3 mol% yttria- partially stabilized zirconia (Y-TZP) and Al2O3 doped Y-TZP (Y-TZPA). Y-TZP slip cast compacts were sintered at 1300-1500 degrees C to achieve fully dense samples. The increase in the sintering temperature enhanced the hydrothermal degradation of Y-TZP. Although the average grain size of Y-TZPA sintered at 1500 degrees C was lower than that of Y-TZP, no significant difference in the ageing behavior between these two ceramics was found. For Y-TZP sintered at 1500 degrees C, the volume fraction of monoclinic ZrO2 induced by acid treatment was higher than that obtained after 10 h of hydrothermal treatment The Al2O3 doping of Y-TZP improved the acid degradation resistance. Osteoblast cell culture studies on the Y-TZP surface confirmed its biocompatibility. The Y-TZP surface supported a higher cell proliferation compared to Y-TZPA. The less degradation on the 1 day acid-treated Y-TZPA surface stimulated cell proliferation, whereas a longer acid treatment reduced cell survival. (C) 2015 Elsevier Ltd and Techna Group S.r.l. All rights reserved. (AU)

Processo FAPESP: 12/50949-4 - Progressão de culturas de células osteogênicas sobre cerâmicas bioativas a base de zircônia e fluorapatita
Beneficiário:Paulo Tambasco de Oliveira
Modalidade de apoio: Auxílio à Pesquisa - Regular