| Texto completo | |
| Autor(es): |
Popi, Ana Flavia
;
Ghosn, E
;
Rothstein, TL
;
Herzenberg, LA
;
Holodick, NE
Número total de Autores: 5
|
| Tipo de documento: | Artigo Científico |
| Fonte: | B-1 CELL DEVELOPMENT AND FUNCTION; v. 1362, p. 12-pg., 2015-01-01. |
| Resumo | |
The relationship between malignant B cells and macrophages has long been established. Furthermore, evolutionary studies have demonstrated that B cells from early vertebrates have both phagocytic and antibody production capabilities. In addition to their lymphoid nature, B-1 cells retain several myeloid characteristics. Various reports have demonstrated that B-1 cells can differentiate into phagocytes. However, descriptions of B-1 cells as a novel phagocyte cell member are rarely found in the literature. This review aims to present the available data regarding B-1 cell-derived phagocytes and also discusses how their existence might be relevant to hematopoiesis and immune responses. (AU) | |
| Processo FAPESP: | 08/58561-0 - Células B-1 na embriologia, diferenciação e imunomodulação |
| Beneficiário: | Mario Mariano |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 08/55526-9 - Participação da via Wnt/beta-catenina na diferenciação e auto-renovação de células B-1 |
| Beneficiário: | Ana Flavia Popi |
| Modalidade de apoio: | Auxílio à Pesquisa - Jovens Pesquisadores |