Chemometric cleanup to eliminate ionic liquid interferences and enable its application on in-situ IL-DLLME using HPLC-DAD detection

Autor(es)

Alves de Souza, Fernando Luciano ; de Souza Ramos, Talita Jordanna ; Montenegro, Maria Conceicao B. S. M. ; Pinto, Licarion ; Cassol, Tania Maria ; Silveira Paim, Ana Paula

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF MOLECULAR LIQUIDS; v. 330, p. 6-pg., 2021-02-19.

Resumo

When ionic liquids are used as extractor solvents followed by chromatographic analyses, they might become serious interferents and even unable the analytical determinations. In this work, a chemometric approach based on an analytical curve resolution algorithm was used for mathematical cleanup to eliminate the interferences from the ionic liquid (IL) used in the extraction method (IL-DLLME). Where the in-situ synthesis of the IL and the extraction of the analytes occurred simultaneously. The chemometric approach makes possible the use of many ionic liquids as extractor solvents regardless their interference on the analytical signals and has been applied successfully for the mathematical separation of the haloanisoles' analytical signals in spiked samples of wine from the interferences of the IL with high predictability, presenting linear correlation coefficients of about 0.999. It was possible to highlight the interference of the IL on the measured area of the analytes, specially for dicloroanisole (DCA) from the sample of red wine 2, meaning that, where the interference was stronger the best results were obtained after applying the chemometric approach. (C) 2021 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 14/50951-4 - INCT 2014: Tecnologias Analíticas Avançadas
• Beneficiário: Celio Pasquini
• Modalidade de apoio: Auxílio à Pesquisa - Temático