Effects of Mindfulness-Based Relapse Prevention on the Chronic use of Hypnotics in Treatment-Seeking Women with Insomnia: a Randomized Controlled Trial

Autor(es)

Barros, Viviam Vargas ; Opaleye, Emerita Satiro ; Demarzo, Marcelo ; Curado, Daniela Fernandez ; Bowen, Sarah ; Hachul, Helena ; Noto, Ana Regina

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE; v. 29, n. 3, p. 12-pg., 2021-05-19.

Resumo

Background Hypnotics are one of the most frequently prescribed drugs worldwide, especially for women, and their chronic use may lead to tolerance, dosage escalation, dependence, withdrawal syndrome, and cognitive impairments, representing a significant public health problem. Consistent evidence from previous studies shows benefits of mindfulness-based interventions (MBIs) for substance use disorders (SUD) and insomnia. However, to date, there is a lack of research about effects of MBIs on reduction/cessation of chronic hypnotic use among women with insomnia. Method The present randomized trial evaluated the efficacy of the 8-week group-delivered mindfulness-based relapse prevention (MBRP) program in an intervention group (IG, n = 34) compared with weekly phone monitoring only in the control group (CG, n = 36) in reducing hypnotic use and insomnia severity over a 6-month follow-up period. Results There were significant differences between groups at baseline regarding hypnotic use but not insomnia. Group effects on hypnotic use were found immediately after the intervention (bT1 = 2.01, p < 0.001) and at the 2-month follow-up (bT2 = 2.21, p < 0.001), favoring the IG. The IG also had a greater reduction from baseline levels than the control group in insomnia severity at the 4-month (bT3 = 0.21, p = 0.045) and 6-month (bT4 = 0.32, p = 0.002) follow-ups. Conclusions The findings provide preliminary evidence of benefits of MBRP for reducing insomnia severity and potentially chronic hypnotic use. However, IG effects on chronic hypnotic use may have resulted from IG and control group differences in chronic hypnotic use at baseline. (AU)

• Processo FAPESP: 13/20367-6 - Avaliação do programa Mindfulness-Based Relapse Prevention (MBRP) para a redução e/ou cessação do uso crônico de benzodiazepínicos para indução do sono entre mulheres
• Beneficiário: Víviam Vargas de Barros
• Modalidade de apoio: Bolsas no Brasil - Doutorado