| Texto completo | |
| Autor(es): |
Amaral, Marina Fuzette
;
Casatti, Claudio Aparecido
;
Naqvi, Afsar Raza
;
Lourenco Debortoli, Caio Vinicius
;
Brandini, Daniela Atili
Número total de Autores: 5
|
| Tipo de documento: | Artigo Científico |
| Fonte: | SAUDI DENTAL JOURNAL; v. 36, n. 2, p. 7-pg., 2024-02-19. |
| Resumo | |
Background: This study evaluated the influence of traumatic occlusion in the dentin-pulp complex a molar teeth submitted to subluxation. Material and methods: Ninety Wistar rats were divided into groups Naive (N), Subluxation (S) and Subluxation with traumatic occlusion (STO) and submitted to histological analysis after 7 and 21 days. A quantitative analysis was submitted to one-way ANOVA and Tukey's post-hoc test, and Chi-square and Bonferronis post-hoc test. Results: S and STO showed a significant increase in blood vessels area (p < 0.0005), amorphous fundamental substance (p < 0.0005) and reactionary dentin formation (p < 0.0005), as well as a decrease in the nuclear profile (p < 0.0005), odontoblast layer (p = 0.013 and p < 0.0005) by day 7 when compared with N. These changes normalized by day 21, except for the reactionary dentin (p < 0.0005) in both S and STO groups. Interestingly, the STO group exhibited significant changes in the increase of pulp calcification (p < 0.0005), presence of tubules with nuclei (p < 0.0005), and inflammatory infiltrate (p < 0.0005), as well reduction of nuclear profile (p < 0.0005), odontoblast layer (p < 0.0005) compared with N and S at day 21. Conclusions: STO impaired the defence response and decreased pulp regeneration capacity by increasing the inflammatory infiltrate and pulp calcification, and decreasing the nucleated cell number in the odontoblast layer and central pulp. (AU) | |
| Processo FAPESP: | 12/03067-6 - Expressão das teneurinas (TEN) e dos peptídeos associados ao terminal carboxila das teneurinas (TCAP) no sistema nervoso central primatas não-humanos (Cebus apella) |
| Beneficiário: | Cláudio Aparecido Casatti |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |