Transformative nanobioplasmonic effects: Toxicological implications of plasmonic silver nanoparticles in aquatic biological models

Autor(es)

Queiroz, Lucas G. ; Faustino, Leandro A. ; de Oliveira, Paulo F. M. ; Pompeo, Marcelo ; de Torresi, Susana I. Cordoba

• Tipo de documento: Artigo Científico
• Fonte: Science of The Total Environment; v. 954, p. 11-pg., 2024-10-01.

Resumo

Silver nanoparticles (AgNPs) present unique properties, such as the induced localized surface plasmon resonance (LSPR) provoked under illumination with a proper wavelength, allowing these nanomaterials to be applied in fields such as catalysis and biomedicine. The study of AgNPs is also highly relevant from the environmental pollution viewpoint due to their high production and application in commercial products. Consequently, AgNPs reach aquatic environments and can be plasmonically stimulated under natural light conditions. This study investigates the toxic effects promoted by AgNPs under plasmonic excitation on the survival and physiology of the crustacean Daphnia similis. . Two AgNP shapes (spherical and triangular) with plasmon bands absorbing in different spectral regions in the visible range were studied. The organisms were exposed to different AgNP concentrations under five different light conditions. Survival and changes in enzymatic biomarkers of oxidative stress and lipid storage were evaluated. Under LSPR conditions, we observed increased lethality for both AgNP shapes. LSPR effects of AgNPs showed mortality 2.6 and 1.7 times higher than the treatment under dark conditions for spherical and triangular morphologies respectively. The enzymatic assays demonstrated that plasmonic treatments triggered physiological responses. Significantly decreased activities were observed exclusively under LSPR conditions for both AgNP shapes. Considering all treatments, spherical AgNPs showed lower LC50 50 values than triangular ones, indicating their higher toxic potential. Our results demonstrate that LSPR AgNPs can induce biological responses associated with oxidative stress and survival. Therefore, this study highlights the potential risks of environmental contamination by plasmonically active metallic nanomaterials. These materials can enhance their toxicity when light-excited, yet the results also indicate promising opportunities for light-based therapies. (AU)

• Processo FAPESP: 21/00675-4 - Arquitetura de materiais para armazenamento de energia eletroquímica e catálise
• Beneficiário: Roberto Manuel Torresi
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 22/13146-2 - Biomateriais baseados em polímeros condutores biodegradáveis e bionanoplasmônica
• Beneficiário: Lucas Gonçalves Queiroz
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 20/14955-6 - Desenvolvendo uma nova geração de materiais avançados multicomponentes via síntese mecanoquímica
• Beneficiário: Paulo Filho Marques de Oliveira
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 22/04604-7 - Contribuições plasmônicas na co-eletrolise de N2 e CO2
• Beneficiário: Leandro Augusto Faustino
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 18/13492-2 - Arcabouços sintéticos e naturais aplicados à medicina regenerativa
• Beneficiário: Luiz Henrique Catalani
• Modalidade de apoio: Auxílio à Pesquisa - Temático