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Autor(es):
Marques, Deyvid Novaes ; Piotto, Fernando Angelo ; Azevedo, Ricardo Antunes
Número total de Autores: 3
Tipo de documento: Artigo Científico
Fonte: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; v. 25, n. 22, p. 14-pg., 2024-11-01.
Resumo

With the increasing concern on heavy metal contamination in agriculture and other environmental settings, unraveling the mechanisms of cadmium (Cd) tolerance and response in plants has become highly important. Ongoing plant Cd research over the years has focused on strategic and relevant aspects, including molecular, biochemical, and physiological processes. From this perspective, phosphoproteomics appears to be an innovative and powerful approach to investigating plant responses to Cd stress. Here, we summarize progress in plant Cd research across different plant species regarding large-scale phosphoproteomic investigations. Some studies revealed major proteins participating in detoxification, stress signaling, and metabolism, along with their regulation through phosphorylation, which modulates the plant's defense against Cd. However, many pathways remain unexplored. Expanding these studies will help our ability to alleviate Cd stress and provide further information concerning involved mechanisms. Our purpose is to inspire researchers to further explore the use of phosphoproteomics in unraveling such complex mechanisms of Cd tolerance and response across various plant species, with the ultimate aim of enhancing strategies for mitigating Cd stress in agriculture and polluted environments. (AU)

Processo FAPESP: 20/12666-7 - Modulação tecido-específica do proteoma, da síntese de fitoquelatinas e da atividade de enzimas antioxidantes de tomateiro em resposta ao Cd, utilizando enxertias recíprocas
Beneficiário:Deyvid Novaes Marques
Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
Processo FAPESP: 22/11018-7 - Metabolômica para resposta ao estresse induzido por cádmio: Foco em plantas de tomateiro enxertadas
Beneficiário:Deyvid Novaes Marques
Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Pós-Doutorado