| Texto completo | |
| Autor(es): |
Sanches, Ana Leticia Madeira
;
Pinto, Thandy Junio da Silva
;
Daam, Michiel Adriaan
;
Teresa, Fabricio Barreto
;
Vieira, Bruna Horvath
;
Reghini, Marina Vanderlei
;
de Almeida, Eduardo Alves
;
Espindola, Evaldo Luiz Gaeta
Número total de Autores: 8
|
| Tipo de documento: | Artigo Científico |
| Fonte: | AQUATIC TOXICOLOGY; v. 273, p. 8-pg., 2024-06-12. |
| Resumo | |
Pesticides are released into the environment daily, and their effects on nontarget species in aquatic ecosystems have been widely reported. To evaluate the adverse effects caused in adults of Danio rerio species exposed to the pesticides abamectin, difenoconazole, and their commercial formulations (Kraft 36EC (R) and Score 250EC (R)), both isolated and in mixtures, biochemical biomarkers were analyzed in the gills of organisms exposed to sublethal concentrations. To this end, the activities of the enzymes 7-ethoxyresorufin-O-deethylase (EROD), glucuronosyltransferase (UDPGT), glutathione-S-transferase (GST), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), lipid hydroperoxide (LH), and malondialdehyde (MDA), which are indicative of oxidative stress, were measured after 48 h of exposure to the different pesticide treatments. The results showed a significant increase in EROD activity and MDA levels in the gills of fish exposed to the commercial formulation of abamectin. When the fish were exposed to difenoconazole and its commercial formulation, an increase in GST, GPx, and MDA levels and a decrease in GR activity were observed in the gills. Furthermore, the responses of the biomarkers were more pronounced in organisms exposed to mixtures of both active ingredients and commercial formulations. It is concluded that the commercial formulations Kraft 36EC (R) and Score 250EC (R) and their mixtures cause significant alterations in the detoxification metabolism of exposed organisms and induce oxidative stress in fish. (AU) | |
| Processo FAPESP: | 22/12104-4 - Destino e impactos de microplásticos e pesticidas em matrizes aquáticas e terrestres em contextos agrícolas |
| Beneficiário: | Cassiana Carolina Montagner |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 14/14621-0 - Análise do efeito ambiental dos praguicidas kraft e score e de seus princípios ativos abamectina e difenoconazol em águas superficiais tropicais por meio de biomarcadores |
| Beneficiário: | Ana Letícia Madeira Sanches |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 17/05543-3 - Estudo comparativo dos efeitos tóxicos gerados em embriões e adultos de Danio rerio expostos ao inseticida abamectina e ao fungicida difenoconazol |
| Beneficiário: | Ana Letícia Madeira Sanches |
| Modalidade de apoio: | Bolsas no Exterior - Estágio de Pesquisa - Doutorado |
| Processo FAPESP: | 23/02121-1 - Ecoinovação e ecotoxicologia aplicada ao monitoramento e análise de risco por agrotóxicos do maior remanescente contínuo de Mata Atlântica |
| Beneficiário: | Ana Letícia Madeira Sanches |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 23/02708-2 - SETAC Latin America 15th Biennial Meeting |
| Beneficiário: | Ana Letícia Madeira Sanches |
| Modalidade de apoio: | Auxílio à Pesquisa - Reunião - Exterior |
| Processo FAPESP: | 22/14293-9 - Destino, interação e efeitos ecológicos de microplásticos e agrotóxicos em ambientes de água doce tropicais |
| Beneficiário: | Thandy Júnio da Silva Pinto |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |