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Correlation Between Different Dietary Indexes, and Their Association with An Anti-inflammatory Biomarker in Older Adults: An Exploratory Study

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Autor(es):
Vicente, Beatriz Martins ; Bastos, Amalia Almeida ; de Melo, Camila Maria ; de Aquino, Rita de Cassia ; Ribeiro, Sandra Maria Lima
Número total de Autores: 5
Tipo de documento: Artigo Científico
Fonte: EUROPEAN JOURNAL OF GERIATRICS AND GERONTOLOGY; v. 5, n. 3, p. 8-pg., 2023-12-01.
Resumo

Objective: Aging is associated with low-grade systemic inflammation (LGSI), and nutrition has been recognized as a crucial modifiable factor concerning LGSI. The aims of this study are to (i) identify the dietary quality of community-dwelling older adults using three approaches; two conventional a priori indexes and a ratio between minimally processed and ultra-processed foods (UPR; based on the NOVA classification); (ii) explore some differences and similarities among the approaches; (iii) investigate the association of DII and MDS with a biomarker of systemic inflammation, and investigate if UPR could be used in a complementary way to these associations. Materials and Methods: We studied independent (non-frail) older adults, both genders, without any inflammatory disease. Variables investigated: -The anti-inflammatory index (AII = IL-10/IL-6 ratio); -Two 24h-food recall, from which we calculated: The dietary inflammatory index (DII); the Mediterranean Diet Scale (MDS); and the ratio between unprocessed or minimally processed/ultra-processed food (UPR). Single and multiples linear regression models, crude or adjusted by age and sex, were adopted to test the associations between the approaches and the anti-inflammatory biomarker. The differences and similarities between the approaches were explored using correlation analyses and the regression models. Results: The MDS and DII showed the same trend to indicate the inflammatory potential; the UPR presented a non-significant correlation with the others. Only the MDS positively and significantly explained the AII values; the combination between MDS or DII with UPR did not change the association level with the anti-inflammatory index. Conclusion: The only significant correlation was found between MDS and DII, however in different directions; only the MDS showed a significant association with our anti-inflammatory marker and the inclusion of UPR in our regression models did not add any improvement to the models. More studies are necessary with more robust and representative samples. (AU)

Processo FAPESP: 12/15976-0 - Efeito da suplementação nutricional sobre a permeabilidade intestinal, a inflamação sistêmica e consequências na composição corporal de idosos
Beneficiário:Sandra Maria Lima Ribeiro
Modalidade de apoio: Auxílio à Pesquisa - Regular
Processo FAPESP: 19/24213-0 - Transtornos mentais comuns, adesão ao padrão da dieta mediterrânea e perfil lipídico de idosos residentes no município de São Paulo nos anos de 2003, 2008 e 2015
Beneficiário:Amália Almeida Bastos
Modalidade de apoio: Bolsas no Brasil - Doutorado