| Texto completo | |
| Autor(es): |
Goulart, Gassia da Luz
;
Agostoni, Piergiuseppe
;
Salvioni, Elisabetta
;
Silva, Rebeca Nunes
;
Bassi-Dibai, Daniela
;
Roscani, Meliza Goi
;
Arena, Ross
;
Myers, Jonathan
;
Borghi-Silva, Audrey
Número total de Autores: 9
|
| Tipo de documento: | Artigo Científico |
| Fonte: | HEART & LUNG; v. 65, p. 5-pg., 2024-02-24. |
| Resumo | |
Background: While patients with heart failure (HF) with reduced left ventricular ejection fraction (HFrEF) constitutes a global health crisis the incidence, prevalence and prognosis of the disease may differ depending on the continent and country. Objective: To profile, analyze and compare cardiopulmonary exercise testing (CPET) data of patients with HFrEF between Italian and Brazilian cohorts. Methods: In this observational study, a total of 630 patients with clinical and functional diagnosis of HFrEF (315 patients from Brazil and 315 patients from Italy) performed CPET. Results: Although Brazilian patients were slightly younger (Brazil 60 +/- 10 vs Italy 64 +/- 11 p<0.001) with a better peak oxygen consumption (VO2), circulatory power and left ventricular ejection fraction (LVEF) (p<0.01), ventilatory inefficiency and oscillation ventilation was higher when compared to the Italian cohort. When stratifying patients with LVEF <= 30 % and age >= 60 years, Brazilian patients presented worse ventilatory efficiency, and lower peak VO2 compared to the Italian cohort. Conclusion: Patients with HFrEF from Brazil exhibited higher ventilatory inefficiency and a greater prevalence of oscillatory ventilation during CPET compared to patients with the same diagnosis from Italy. (AU) | |
| Processo FAPESP: | 20/13465-5 - Identificação de variáveis prognósticas do teste de exercício cardiopulmonar para estratificar gravidade da insuficiência cardíaca |
| Beneficiário: | Cássia da Luz Goulart |
| Modalidade de apoio: | Bolsas no Exterior - Estágio de Pesquisa - Doutorado Direto |
| Processo FAPESP: | 18/03233-0 - Estudo da interação cardiorrespiratória e da oferta de oxigênio periférica e cerebral como moduladores da capacidade de exercício durante a aplicação do binível na coexistência da DPOC-ICC |
| Beneficiário: | Cássia da Luz Goulart |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado Direto |