Can cell-cultured meat from stem cells pave the way for sustainable alternative protein?

Autor(es)

Nunes, Octavio Bignardi da Silva ; Buranello, Tiago Willian ; Farias, Fabiana de Andrade ; Rosero, Jenyffer ; Recchia, Kaiana ; Bressan, Fabiana Fernandes

• Tipo de documento: Artigo Científico
• Fonte: CURRENT RESEARCH IN FOOD SCIENCE; v. 10, p. 12-pg., 2025-01-01.

Resumo

As the global population grows, the demand for food and animal-derived products rises significantly, posing a notable challenge to the progress of society in general. Alternative protein production may adequately address such a challenge, and cell-based meat production emerges as a promising solution. This review investigates methodologies for in vitro myogenesis and adipogenesis from stem cells (adult, embryonic, or induced pluripotent stem cells- iPSCs) across different animal species, as well as the remaining challenges for scalability, the possibility of genetic modification, along with safety concerns regarding the commercialization of cell-cultured meat. Regarding such complexities, interdisciplinary approaches will be vital for assessing the potential of cell-cultured meat as a sustainable protein source, mimicking the sensory and nutritional attributes of conventional livestock meat whilst meeting the demands of a growing global population while mitigating environmental impacts. (AU)

• Processo FAPESP: 24/19758-5 - Geração de células musculares in vitro a partir de células-tronco pluripotentes induzidas na espécie bovina
• Beneficiário: Tiago William Buranello
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 23/16931-5 - Reprogramação de fibroblastos de tilápia do Nilo (Oreochromis niloticus) em células de pluripotência induzida
• Beneficiário: Fabiana de Andrade Farias
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
• Processo FAPESP: 23/00480-4 - Diferenciação de células iPS suínas (Sus domesticus) e corpos embrióides derivados destas em células osteogênicas, adipogênicas e condrogênicas
• Beneficiário: Octavio Bignardi da Silva Nunes
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica