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Mezzina, Ana Ligia Braga
;
Pereira, Erick Marlon
;
de Melo, Cecilia Archangelo Ferreira
;
Souza, Thallysson Taumaturgo Silva
;
Monteiro, Matheus Saliba
;
Poor, Andre Pegoraro
;
Muro, Bruno Bracco Donatelli
;
Veloso, Caroline
;
Coelho, Flavio de Aguiar
;
Carnevale, Rafaella Fernandes
;
Pereira, Francisco Alves
;
dos Santos, Fernanda Mariane
;
Martinez, Jose Alfonso Echavarria
;
Messias, Rodrigo Knop Guazzi
;
Garbossa, Cesar Augusto Pospissil
Número total de Autores: 15
|
| Tipo de documento: | Artigo Científico |
| Fonte: | VETERINARY RESEARCH COMMUNICATIONS; v. 49, n. 4, p. 12-pg., 2025-08-01. |
| Resumo | |
Organic acids are increasingly being investigated as alternatives to zinc oxide (ZnO) in nursery pig diets. Monoglycerides can act in distal parts of the intestine, promoting intestinal health, also reducing bacterial fermentation in hindgut. This study aimed to determine the effects of dietary supplementation based on a blend of monoglycerides (C4:C8:C10) (MBLEND) in replacement to ZnO during the nursery phase on growth-performance and intestinal health. Ninety-six piglets were used (average weight 7.08 +/- 0.837 kg) with 25 days of age during 42 days, divided into three treatments and eight replicates in a randomized block design. The treatments were: CON - Negative control (basal diet without additive supplementation); MBLEND - Fatty acids (basal diet with monoglycerides blend (C4:C8:C10) additive supplementation at 1.5 kg/ton in the pre-initial 1 and pre-initial 2 phases, 1.0 kg/ton in the initial 1 and initial 2 phases) and ZnO - Zinc oxide (basal diet with zinc oxide supplementation at 3000 ppm in the pre-initial 1, pre-initial 2 and initial 1 phases, 2000 ppm in the initial 2 phase). Both ZnO and MBLEND groups did not influence (P>0.05) growth performance during all phases. The inclusion of the MBLEND improved (P<0.05) dry matter (DM), crude protein (CP), and ashes digestibility when compared to CON and ZnO groups. The use of ZnO reduced (P<0.05) IL-1 beta cytokine expression in the piglets' jejunal mucosa. ZnO increased evenness and affected beta-diversity (P<0.05) compared to CON and MBLEND. The ZnO group increased Tannerellaceae, Bacteroidaceae, and Muribaculaceae families and reduced Escherichia Coli-Shigella and Desulfovibrio generas (q<0.05). Although there were similar results on growth performance, ZnO modulated cecal microbiota and reduced inflammatory ileal cytokines and MBLEND improved protein and ashes digestibility. (AU) | |
| Processo FAPESP: | 23/08227-6 - Glicinato de zinco como fonte alternativa ao óxido de zinco em dietas de leitões em fase de creche |
| Beneficiário: | Cecília Archangelo Ferreira de Melo |
| Modalidade de apoio: | Bolsas no Brasil - Iniciação Científica |
| Processo FAPESP: | 23/18259-2 - Diferentes relações cálcio-fósforo associadas à utilização de vitamina D na dieta de suínos em fase de crescimento e terminação |
| Beneficiário: | Fernanda Mariane dos Santos |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |