| Texto completo | |
| Autor(es): |
dos Santos, Lucas N.
;
Cavalcante, Lidia do N.
;
Rocha, Dhiovanna C.
;
Prado, Guilherme S.
;
Coletta-Filho, Helvecio D.
;
de Souza, Alessandra A.
Número total de Autores: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | PHYTOFRONTIERS; v. 5, n. 1, p. 12-pg., 2025-03-01. |
| Resumo | |
N-acetylcysteine (NAC), an amino acid naturally found in Allium plants, is well known for its health benefits in humans. However, its potential applications in plant health remain underexplored, especially considering that, although thousands of studies are published annually in clinical research, fewer than 10 focus on its use in plants each year. This review consolidates recent findings on the role of NAC as a potent antioxidant molecule in mitigating both biotic and abiotic stresses in plants, highlighting its valuable contributions to sustainable agriculture. NAC reduces oxidative stress by directly scavenging reactive oxygen species and indirectly increasing cysteine and glutathione levels, both critical for cellular defense responses. Moreover, NAC breaks intramolecular and intermolecular disulfide bonds in thiolated proteins, potentially further enhancing its antioxidant effects by releasing free thiols. It also functions as a chelating agent, binding to heavy metals and reducing their toxicity. Furthermore, NAC's efficacy in controlling bacterial infections in humans and animals-through mechanisms such as disrupting disulfide bonds in extracellular proteins and breaking down biofilm matrices-has been shown to extend to plant pathosystems, where it aids in suppressing bacterial pathogens. In addition to stress alleviation, NAC has been demonstrated to enhance crop productivity, improve food quality, and offer ecological benefits by promoting the health of pollinators and free-living soil organisms. These multifaceted attributes highlight NAC's potential as a key tool in agriculture, helping to improve plant resilience, support ecosystem balance, and advance sustainable crop management practices. (AU) | |
| Processo FAPESP: | 22/10505-1 - Abordagens de Engenharia Genética e Biologia Sintética aplicadas ao desenvolvimento de novas variedades de laranja doce (Citrus sinensis) resistentes ou tolerantes ao Huanglongbing (HLB) |
| Beneficiário: | Guilherme Souza Prado |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |
| Processo FAPESP: | 23/05118-1 - Potencial das plantas de citros geneticamente modificadas supexpressando o gene rpfF no controle de doenças bacterianas de citros. |
| Beneficiário: | Alessandra Alves de Souza |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 21/03466-7 - Edição de genes de Citrus sinensis visando atenuar o acúmulo de caloses associadas aos sintomas do Huanglongbing (HLB) |
| Beneficiário: | Dhiôvanna Corrêia Rocha |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 14/50880-0 - INCT 2014: de genômica comparativa e funcional e melhoramento assistido de citros |
| Beneficiário: | Marcos Antonio Machado |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 22/12483-5 - Sistema CRISPR/Cas9 na edição do gene Sieve Element Occlusion c (SEOc), visando obtenção de plantas de citros tolerantes ao Huanglongbing (HLB) |
| Beneficiário: | Lucas Nascimento dos Santos |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |